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• W2074877897 abstract "Due to the small size of most nerve terminals, the ion channels which underlie presynaptic currents are usually inaccessible to investigation by conventional electrophysiological techniques. Here we describe a simple method for obtaining single-channel recordings from synaptic plasma membranes that does not require exposure of the native membranes to exogenous lipids or fusogens. To illustrate the method, we have recorded single-channel activity from rat cerebrocortical synaptosomal membranes. Under conditions designed to isolate calcium-independent currents, we describe three channel types that are most commonly observed." @default.
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• W2074877897 date "1993-08-01" @default.
• W2074877897 modified "2023-10-16" @default.
• W2074877897 title "A simple method for recording single-channel activity from synaptic plasma membranes" @default.
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• W2074877897 doi "https://doi.org/10.1016/0165-0270(93)90111-4" @default.
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