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• W2074920686 endingPage "e45972" @default.
• W2074920686 startingPage "e45972" @default.
• W2074920686 abstract "Magnetic resonance imaging studies have reported significant functional and structural differences between depressed patients and controls. Little attention has been given, however, to the abnormalities in anatomical connectivity in depressed patients. In the present study, we aim to investigate the alterations in connectivity of whole-brain anatomical networks in those suffering from major depression by using machine learning approaches. Brain anatomical networks were extracted from diffusion magnetic resonance images obtained from both 22 first-episode, treatment-naive adults with major depressive disorder and 26 matched healthy controls. Using machine learning approaches, we differentiated depressed patients from healthy controls based on their whole-brain anatomical connectivity patterns and identified the most discriminating features that represent between-group differences. Classification results showed that 91.7% (patients=86.4%, controls=96.2%; permutation test, p<0.0001) of subjects were correctly classified via leave-one-out cross-validation. Moreover, the strengths of all the most discriminating connections were increased in depressed patients relative to the controls, and these connections were primarily located within the cortical-limbic network, especially the frontal-limbic network. These results not only provide initial steps toward the development of neurobiological diagnostic markers for major depressive disorder, but also suggest that abnormal cortical-limbic anatomical networks may contribute to the anatomical basis of emotional dysregulation and cognitive impairments associated with this disease." @default.
• W2074920686 created "2016-06-24" @default.
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• W2074920686 date "2012-09-26" @default.
• W2074920686 modified "2023-09-24" @default.
• W2074920686 title "Increased Cortical-Limbic Anatomical Network Connectivity in Major Depression Revealed by Diffusion Tensor Imaging" @default.
• W2074920686 cites W1608071409 @default.
• W2074920686 cites W1665095741 @default.
• W2074920686 cites W1969852349 @default.
• W2074920686 cites W1972412818 @default.
• W2074920686 cites W1973587070 @default.
• W2074920686 cites W1985168009 @default.
• W2074920686 cites W1986014162 @default.
• W2074920686 cites W1986906282 @default.
• W2074920686 cites W1987528796 @default.
• W2074920686 cites W1994414964 @default.
• W2074920686 cites W1999747287 @default.
• W2074920686 cites W2000133863 @default.
• W2074920686 cites W2000591045 @default.
• W2074920686 cites W2006091191 @default.
• W2074920686 cites W2006096283 @default.
• W2074920686 cites W2008753452 @default.
• W2074920686 cites W2010001739 @default.
• W2074920686 cites W2011099767 @default.
• W2074920686 cites W2011140471 @default.
• W2074920686 cites W2013336473 @default.
• W2074920686 cites W2013644296 @default.
• W2074920686 cites W2014050522 @default.
• W2074920686 cites W2026820213 @default.
• W2074920686 cites W2027721376 @default.
• W2074920686 cites W2029362415 @default.
• W2074920686 cites W2032008710 @default.
• W2074920686 cites W2032468815 @default.
• W2074920686 cites W2034828930 @default.
• W2074920686 cites W2038068277 @default.
• W2074920686 cites W2040253915 @default.
• W2074920686 cites W2041583787 @default.
• W2074920686 cites W2052644075 @default.
• W2074920686 cites W2053126345 @default.
• W2074920686 cites W2053186076 @default.
• W2074920686 cites W2053756137 @default.
• W2074920686 cites W2056999109 @default.
• W2074920686 cites W2058046532 @default.
• W2074920686 cites W2060731572 @default.
• W2074920686 cites W2063404606 @default.
• W2074920686 cites W2064000597 @default.
• W2074920686 cites W2066532565 @default.
• W2074920686 cites W2071881327 @default.
• W2074920686 cites W2075971518 @default.
• W2074920686 cites W2083969692 @default.
• W2074920686 cites W2085394612 @default.
• W2074920686 cites W2095438393 @default.
• W2074920686 cites W2100122991 @default.
• W2074920686 cites W2102748276 @default.
• W2074920686 cites W2106614830 @default.
• W2074920686 cites W2109132758 @default.
• W2074920686 cites W2111456519 @default.
• W2074920686 cites W2112423489 @default.
• W2074920686 cites W2114613490 @default.
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• W2074920686 cites W2116136260 @default.
• W2074920686 cites W2120895215 @default.
• W2074920686 cites W2122384242 @default.
• W2074920686 cites W2122562515 @default.
• W2074920686 cites W2123722617 @default.
• W2074920686 cites W2125197046 @default.
• W2074920686 cites W2126081763 @default.
• W2074920686 cites W2131181615 @default.
• W2074920686 cites W2133371501 @default.
• W2074920686 cites W2133710105 @default.
• W2074920686 cites W2136395604 @default.
• W2074920686 cites W2136857108 @default.
• W2074920686 cites W2137640133 @default.
• W2074920686 cites W2142059961 @default.
• W2074920686 cites W2142711129 @default.
• W2074920686 cites W2144364957 @default.
• W2074920686 cites W2144538553 @default.
• W2074920686 cites W2146146069 @default.
• W2074920686 cites W2146873141 @default.
• W2074920686 cites W2147969224 @default.
• W2074920686 cites W2153156486 @default.
• W2074920686 cites W2153734301 @default.
• W2074920686 cites W2154054253 @default.
• W2074920686 cites W2159929956 @default.
• W2074920686 cites W2168372372 @default.
• W2074920686 cites W2319230935 @default.
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• W2074920686 doi "https://doi.org/10.1371/journal.pone.0045972" @default.
• W2074920686 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3458828" @default.
• W2074920686 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23049910" @default.
• W2074920686 hasPublicationYear "2012" @default.
• W2074920686 type Work @default.

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