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- W2074927384 abstract "Abstract The role of protein phosphorylation in the extension of neurites and appearance of microtubular structures in neuroblastoma cells has been investigated by comparing 32P phosphoprotein labeling and protein kinase activity of cells growing in suspension and monolayer cultures. Growth of neuroblastoma cells in monolayer is, in fact, accompanied by neurite out-growth, whereas neurites are absent in cells growing in suspension. The rate of 32P labeling of phosphoprotein is not different in the two culture conditions. Protein kinase activity also is the same in the two culture conditions, and very little or no stimulation of kinase activity by cAMP is observed. It is concluded that appearance of microtubular structures observed in monolayer cultures does not depend on an increased level of protein kinase activity." @default.
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- W2074927384 date "1974-09-01" @default.
- W2074927384 modified "2023-09-27" @default.
- W2074927384 title "Neuroblastoma cells in culture: 32P-phosphoprotein labeling and protein kinase activity" @default.
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- W2074927384 doi "https://doi.org/10.1016/0014-4886(74)90205-2" @default.
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