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- W2074928680 abstract "The removal rate of intravenously injected cortisol has been determined in normal and “stressed” dogs. Normal or decreased removal rates of cortisol were found in all “stress” conditions investigated. Mechanisms other than increased “utilization” of adrenal steroids might therefore be responsible for augmented ACTH secretion in conditions of “stress.” Various theories which might explain why intravenously given cortisol is removed more slowly in severely “stressed” dogs are discussed. ACENTRAL point in the physiology of the adrenal cortex is its function during conditions of “stressful” nature. It appears from the literature that many such conditions are associated with an increase in plasma levels of 17-hydroxycorticosteroids (17-OHCS) (1, 2). Little is known, however, concerning the immediate causes of increases. It has been postulated (3) that during “stress,” the metabolism or “utilization” of adrenal steroids may be increased. Since this would result in a reduction of the concentration of adrenal ste..." @default.
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- W2074928680 date "1958-07-01" @default.
- W2074928680 modified "2023-09-27" @default.
- W2074928680 title "METABOLISM OF CORTISOL IN NORMAL AND “STRESSED” DOGS1" @default.
- W2074928680 doi "https://doi.org/10.1210/endo-63-1-82" @default.
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