FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074929780> ?p ?o ?g. }

• W2074929780 endingPage "4068" @default.
• W2074929780 startingPage "4064" @default.
• W2074929780 abstract "The ability of interferons to reduce cell proliferation in vitro and in vivo is a well-studied phenomenon. To extend such observations, the effect of interferons on the invasiveness in vitro of human malignant cells derived from a Ewing sarcoma was evaluated. Two related parameters were examined: ( i ) production of type IV (basement membrane) collagenase and ( ii ) penetration of human amnion basement membrane and collagenous stroma. After 6 days of treatment with crude fibroblast, leukocyte, or lymphoblastoid interferon at 100 units/ml in serum-free medium, type IV collagenase levels increased 2- to 4-fold per cell relative to those of untreated controls. With homogeneous fibroblast and lymphoblastoid interferons, a 2-fold elevation in type IV collagenase was detected after 2 days, with further increases, occasionally dramatic, occurring on the 4th and 6th day of treatment. The ability of Ewing sarcoma cells to invade human amnion connective tissue was measured after 6 days of treatment with various interferons. Relative to the behavior of untreated controls, crude leukocyte interferon, homogeneous lymphoblastoid interferon, and homogeneous fibroblast interferon at 100 units/ml augmented invasiveness 3-, 17- and 22-fold, respectively, when cells were allowed 4 days in which to traverse the amnion. When untreated cells were exposed simultaneously to the amnion and to homogeneous lymphoblastoid or fibroblast interferon, a 4- to 5-fold increase in invasiveness above control levels was observed in 2 days. These data emphasize the complexity of interferon-induced phenomena. In any overview, the effects of interferon on both the tumor cell and the host must be considered." @default.
• W2074929780 created "2016-06-24" @default.
• W2074929780 creator A5009405751 @default.
• W2074929780 creator A5017208495 @default.
• W2074929780 creator A5051096565 @default.
• W2074929780 creator A5060011933 @default.
• W2074929780 creator A5068017484 @default.
• W2074929780 creator A5086886026 @default.
• W2074929780 date "1982-07-01" @default.
• W2074929780 modified "2023-09-25" @default.
• W2074929780 title "Interferon enhancement of the invasive capacity of Ewing sarcoma cells <i>in vitro</i>" @default.
• W2074929780 cites W1524834942 @default.
• W2074929780 cites W1542215200 @default.
• W2074929780 cites W1589608483 @default.
• W2074929780 cites W1995249913 @default.
• W2074929780 cites W2014043577 @default.
• W2074929780 cites W2018162474 @default.
• W2074929780 cites W2027183556 @default.
• W2074929780 cites W2028389289 @default.
• W2074929780 cites W2047108476 @default.
• W2074929780 cites W2051780676 @default.
• W2074929780 cites W2052870403 @default.
• W2074929780 cites W2057641029 @default.
• W2074929780 cites W2060926084 @default.
• W2074929780 cites W2064127583 @default.
• W2074929780 cites W2079580785 @default.
• W2074929780 cites W2104527114 @default.
• W2074929780 cites W2144360148 @default.
• W2074929780 cites W2151789550 @default.
• W2074929780 cites W2160066962 @default.
• W2074929780 cites W2283622792 @default.
• W2074929780 cites W2290617700 @default.
• W2074929780 cites W2406603782 @default.
• W2074929780 cites W2414340841 @default.
• W2074929780 cites W2418642723 @default.
• W2074929780 doi "https://doi.org/10.1073/pnas.79.13.4064" @default.
• W2074929780 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/346577" @default.
• W2074929780 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6180434" @default.
• W2074929780 hasPublicationYear "1982" @default.
• W2074929780 type Work @default.
• W2074929780 sameAs 2074929780 @default.
• W2074929780 citedByCount "37" @default.
• W2074929780 crossrefType "journal-article" @default.
• W2074929780 hasAuthorship W2074929780A5009405751 @default.
• W2074929780 hasAuthorship W2074929780A5017208495 @default.
• W2074929780 hasAuthorship W2074929780A5051096565 @default.
• W2074929780 hasAuthorship W2074929780A5060011933 @default.
• W2074929780 hasAuthorship W2074929780A5068017484 @default.
• W2074929780 hasAuthorship W2074929780A5086886026 @default.
• W2074929780 hasBestOaLocation W20749297801 @default.
• W2074929780 hasConcept C113842279 @default.
• W2074929780 hasConcept C142724271 @default.
• W2074929780 hasConcept C150903083 @default.
• W2074929780 hasConcept C153911025 @default.
• W2074929780 hasConcept C172680121 @default.
• W2074929780 hasConcept C181199279 @default.
• W2074929780 hasConcept C202751555 @default.
• W2074929780 hasConcept C203014093 @default.
• W2074929780 hasConcept C207001950 @default.
• W2074929780 hasConcept C2776178377 @default.
• W2074929780 hasConcept C2776193487 @default.
• W2074929780 hasConcept C2778256501 @default.
• W2074929780 hasConcept C2778394429 @default.
• W2074929780 hasConcept C2779234561 @default.
• W2074929780 hasConcept C2780381497 @default.
• W2074929780 hasConcept C2780646683 @default.
• W2074929780 hasConcept C54355233 @default.
• W2074929780 hasConcept C55493867 @default.
• W2074929780 hasConcept C71924100 @default.
• W2074929780 hasConcept C81885089 @default.
• W2074929780 hasConcept C86803240 @default.
• W2074929780 hasConcept C95444343 @default.
• W2074929780 hasConceptScore W2074929780C113842279 @default.
• W2074929780 hasConceptScore W2074929780C142724271 @default.
• W2074929780 hasConceptScore W2074929780C150903083 @default.
• W2074929780 hasConceptScore W2074929780C153911025 @default.
• W2074929780 hasConceptScore W2074929780C172680121 @default.
• W2074929780 hasConceptScore W2074929780C181199279 @default.
• W2074929780 hasConceptScore W2074929780C202751555 @default.
• W2074929780 hasConceptScore W2074929780C203014093 @default.
• W2074929780 hasConceptScore W2074929780C207001950 @default.
• W2074929780 hasConceptScore W2074929780C2776178377 @default.
• W2074929780 hasConceptScore W2074929780C2776193487 @default.
• W2074929780 hasConceptScore W2074929780C2778256501 @default.
• W2074929780 hasConceptScore W2074929780C2778394429 @default.
• W2074929780 hasConceptScore W2074929780C2779234561 @default.
• W2074929780 hasConceptScore W2074929780C2780381497 @default.
• W2074929780 hasConceptScore W2074929780C2780646683 @default.
• W2074929780 hasConceptScore W2074929780C54355233 @default.
• W2074929780 hasConceptScore W2074929780C55493867 @default.
• W2074929780 hasConceptScore W2074929780C71924100 @default.
• W2074929780 hasConceptScore W2074929780C81885089 @default.
• W2074929780 hasConceptScore W2074929780C86803240 @default.
• W2074929780 hasConceptScore W2074929780C95444343 @default.
• W2074929780 hasIssue "13" @default.
• W2074929780 hasLocation W20749297801 @default.
• W2074929780 hasLocation W20749297802 @default.
• W2074929780 hasLocation W20749297803 @default.

• next