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• W2074933182 abstract "For activation of kidney membrane phospholipase D (PLD), cytosol is absolutely needed in addition to GTP-gamma-S. The active component of cytosol consists of three protein factors: ADP-ribosylation factor, RhoA, and a soluble 36-kDa protein. Any combination of these two factors synergistically activates PLD to some extent, but the presence of the three factors causes full activation. The 36-kDa protein is stable at 60 degrees C but inactivated at 80 degrees C for 10 min. Tissue distribution of the 36-kDa protein roughly coincides with that of PLD, suggesting physiological relevance of the protein in the regulation of PLD." @default.
• W2074933182 created "2016-06-24" @default.
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• W2074933182 date "1996-06-03" @default.
• W2074933182 modified "2023-09-25" @default.
• W2074933182 title "Reconstitution of GTP-γ-S-dependent phospholipase D activity with ARF, RhoA, and a soluble 36-kDa protein" @default.
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• W2074933182 doi "https://doi.org/10.1016/0014-5793(96)00483-8" @default.
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• W2074933182 hasPublicationYear "1996" @default.
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