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- W2074943263 abstract "Biological effects of caspases-1, -2 and -3 have been investigated by transfection of these human cDNAs into activated c-Ha-ras-transformed NIH3T3 mouse fibroblasts. High expression of caspase-2 but not caspase-1 or -3 induced flat revertant cells which lost the ability of anchorage-independent growth. Notably, these revertants contained a reduced amount of Ras protein. These suggest that caspase-2 exhibited a tumor-suppressive activity by affecting the expression level of Ras protein." @default.
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- W2074943263 date "1998-09-01" @default.
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- W2074943263 title "Suppression of Transformed Phenotypes of Ha-ras-Transformed NIH3T3 Cells by Caspase-2" @default.
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- W2074943263 doi "https://doi.org/10.1006/bbrc.1998.9386" @default.
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