FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074953002> ?p ?o ?g. }

• W2074953002 endingPage "6869" @default.
• W2074953002 startingPage "6861" @default.
• W2074953002 abstract "ABSTRACT The nitrogen regulatory protein P II and the ammonia gas channel AmtB are both found in most prokaryotes. Interaction between these two proteins has been observed in several organisms and may regulate the activities of both proteins. The regulation of their interaction is only partially understood, and we show that in Rhodospirillum rubrum one P II homolog, GlnJ, has higher affinity for an AmtB 1 -containing membrane than the other two P II homologs, GlnB and GlnK. This interaction strongly favors the nonuridylylated form of GlnJ and is disrupted by high levels of 2-ketoglutarate (2-KG) in the absence of ATP or low levels of 2-KG in the presence of ATP. ADP inhibits the destabilization of the GlnJ-AmtB 1 complex in the presence of ATP and 2-KG, supporting a role for P II as an energy sensor measuring the ratio of ATP to ADP. In the presence of saturating levels of ATP, the estimated K d of 2-KG for GlnJ bound to AmtB 1 is 340 μM, which is higher than that required for uridylylation of GlnJ in vitro, about 5 μM. This supports a model where multiple 2-KG and ATP molecules must bind a P II trimer to stimulate release of P II from AmtB 1 , in contrast to the lower 2-KG requirement for productive uridylylation of P II by GlnD." @default.
• W2074953002 created "2016-06-24" @default.
• W2074953002 creator A5021162699 @default.
• W2074953002 creator A5079545745 @default.
• W2074953002 creator A5087125917 @default.
• W2074953002 date "2007-10-01" @default.
• W2074953002 modified "2023-09-25" @default.
• W2074953002 title "Specificity and Regulation of Interaction between the P _II and AmtB ₁ Proteins in <i>Rhodospirillum rubrum</i>" @default.
• W2074953002 cites W1545148915 @default.
• W2074953002 cites W1570204973 @default.
• W2074953002 cites W1597085935 @default.
• W2074953002 cites W1673869413 @default.
• W2074953002 cites W1752121003 @default.
• W2074953002 cites W1814229050 @default.
• W2074953002 cites W1820178654 @default.
• W2074953002 cites W1921023646 @default.
• W2074953002 cites W1921390050 @default.
• W2074953002 cites W1969950088 @default.
• W2074953002 cites W1970746458 @default.
• W2074953002 cites W1975085160 @default.
• W2074953002 cites W1976710174 @default.
• W2074953002 cites W1981330997 @default.
• W2074953002 cites W1982830152 @default.
• W2074953002 cites W1983589176 @default.
• W2074953002 cites W1988850184 @default.
• W2074953002 cites W1989895002 @default.
• W2074953002 cites W1993922118 @default.
• W2074953002 cites W1995087505 @default.
• W2074953002 cites W1996349809 @default.
• W2074953002 cites W1996527581 @default.
• W2074953002 cites W1997707728 @default.
• W2074953002 cites W2004720572 @default.
• W2074953002 cites W2014106909 @default.
• W2074953002 cites W2036456099 @default.
• W2074953002 cites W2041123159 @default.
• W2074953002 cites W2044489365 @default.
• W2074953002 cites W2046192658 @default.
• W2074953002 cites W2059071932 @default.
• W2074953002 cites W2063449571 @default.
• W2074953002 cites W2070056713 @default.
• W2074953002 cites W2071288995 @default.
• W2074953002 cites W2084586898 @default.
• W2074953002 cites W2088907022 @default.
• W2074953002 cites W2091473682 @default.
• W2074953002 cites W2094039296 @default.
• W2074953002 cites W2094835963 @default.
• W2074953002 cites W2111560682 @default.
• W2074953002 cites W2112258048 @default.
• W2074953002 cites W2126055452 @default.
• W2074953002 cites W2128471036 @default.
• W2074953002 cites W2134438080 @default.
• W2074953002 cites W2136758639 @default.
• W2074953002 cites W2142418760 @default.
• W2074953002 cites W2144459921 @default.
• W2074953002 cites W2150411102 @default.
• W2074953002 cites W2156723754 @default.
• W2074953002 cites W2161827381 @default.
• W2074953002 cites W2164751533 @default.
• W2074953002 cites W2168421316 @default.
• W2074953002 cites W2338631559 @default.
• W2074953002 doi "https://doi.org/10.1128/jb.00759-07" @default.
• W2074953002 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2045211" @default.
• W2074953002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17644595" @default.
• W2074953002 hasPublicationYear "2007" @default.
• W2074953002 type Work @default.
• W2074953002 sameAs 2074953002 @default.
• W2074953002 citedByCount "33" @default.
• W2074953002 countsByYear W20749530022012 @default.
• W2074953002 countsByYear W20749530022013 @default.
• W2074953002 countsByYear W20749530022014 @default.
• W2074953002 countsByYear W20749530022015 @default.
• W2074953002 countsByYear W20749530022017 @default.
• W2074953002 countsByYear W20749530022018 @default.
• W2074953002 countsByYear W20749530022020 @default.
• W2074953002 countsByYear W20749530022021 @default.
• W2074953002 countsByYear W20749530022023 @default.
• W2074953002 crossrefType "journal-article" @default.
• W2074953002 hasAuthorship W2074953002A5021162699 @default.
• W2074953002 hasAuthorship W2074953002A5079545745 @default.
• W2074953002 hasAuthorship W2074953002A5087125917 @default.
• W2074953002 hasBestOaLocation W20749530022 @default.
• W2074953002 hasConcept C112243037 @default.
• W2074953002 hasConcept C12554922 @default.
• W2074953002 hasConcept C178790620 @default.
• W2074953002 hasConcept C181199279 @default.
• W2074953002 hasConcept C185592680 @default.
• W2074953002 hasConcept C2776403692 @default.
• W2074953002 hasConcept C2777082638 @default.
• W2074953002 hasConcept C2779546866 @default.
• W2074953002 hasConcept C55493867 @default.
• W2074953002 hasConcept C86803240 @default.
• W2074953002 hasConceptScore W2074953002C112243037 @default.
• W2074953002 hasConceptScore W2074953002C12554922 @default.
• W2074953002 hasConceptScore W2074953002C178790620 @default.
• W2074953002 hasConceptScore W2074953002C181199279 @default.
• W2074953002 hasConceptScore W2074953002C185592680 @default.
• W2074953002 hasConceptScore W2074953002C2776403692 @default.
• W2074953002 hasConceptScore W2074953002C2777082638 @default.

• next