FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074967251> ?p ?o ?g. }

• W2074967251 endingPage "400" @default.
• W2074967251 startingPage "394" @default.
• W2074967251 abstract "Abstract Gel delivery vehicles have ideal placement characteristics for periodontal and oral mucosal drug delivery. However, the retention of the vehicle at the site may be of short duration thereby limiting its therapeutic effect. Bioadhesion has received little attention as a means of enhancing vehicle retention in the periodontal pocket and this study aimed to investigate the possible role of this phenomenon to aid oral drug delivery. Chitosan, xanthan gum and poly (ethylene oxide) were selected as potential vehicles from previous in vitro studies, since all 3 had shown good bioadhesive properties. Retention in the periodontal pocket was assessed by means of an insoluble fluorescein marker in 8 patients, and to the oral mucosa by the retention of a small plastic film in 12 subjects. The results showed that fluorescein release from the periodontal pocket was significantly longer for chitosan than for other gels or a water control. In contrast, xanthan gum gave the most prolonged adhesion time on the oral mucosa (153.5 min) followed by poly (ethylene oxide) (89.3 min) and chitosan (42.6 min), and these times were all significantly different from each other (p<0.05). The results from this study would tend to suggest that the bioadhesive properties of an aqueous gel may be directly related to its retention both in the periodontal pocket and on the oral mucosa. However, other important factors for mucosal adhesion include the patient acceptability of the formulation and the choice of application site." @default.
• W2074967251 created "2016-06-24" @default.
• W2074967251 creator A5031953390 @default.
• W2074967251 creator A5070714240 @default.
• W2074967251 creator A5089520411 @default.
• W2074967251 date "1997-06-01" @default.
• W2074967251 modified "2023-09-27" @default.
• W2074967251 title "An investigation of bioadhesion for periodontal and oral mucosal drug delivery" @default.
• W2074967251 cites W1963780471 @default.
• W2074967251 cites W1970882485 @default.
• W2074967251 cites W1987373761 @default.
• W2074967251 cites W2004062180 @default.
• W2074967251 cites W2018997416 @default.
• W2074967251 cites W2025501818 @default.
• W2074967251 cites W2030343589 @default.
• W2074967251 cites W2056922463 @default.
• W2074967251 cites W2072515072 @default.
• W2074967251 cites W2082894345 @default.
• W2074967251 cites W2088670612 @default.
• W2074967251 cites W2090206356 @default.
• W2074967251 cites W2104381799 @default.
• W2074967251 cites W2160541575 @default.
• W2074967251 cites W2165125798 @default.
• W2074967251 cites W2170169002 @default.
• W2074967251 cites W2084708243 @default.
• W2074967251 doi "https://doi.org/10.1111/j.1600-051x.1997.tb00203.x" @default.
• W2074967251 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9205918" @default.
• W2074967251 hasPublicationYear "1997" @default.
• W2074967251 type Work @default.
• W2074967251 sameAs 2074967251 @default.
• W2074967251 citedByCount "69" @default.
• W2074967251 countsByYear W20749672512012 @default.
• W2074967251 countsByYear W20749672512013 @default.
• W2074967251 countsByYear W20749672512014 @default.
• W2074967251 countsByYear W20749672512015 @default.
• W2074967251 countsByYear W20749672512016 @default.
• W2074967251 countsByYear W20749672512018 @default.
• W2074967251 countsByYear W20749672512019 @default.
• W2074967251 countsByYear W20749672512020 @default.
• W2074967251 countsByYear W20749672512021 @default.
• W2074967251 countsByYear W20749672512022 @default.
• W2074967251 countsByYear W20749672512023 @default.
• W2074967251 crossrefType "journal-article" @default.
• W2074967251 hasAuthorship W2074967251A5031953390 @default.
• W2074967251 hasAuthorship W2074967251A5070714240 @default.
• W2074967251 hasAuthorship W2074967251A5089520411 @default.
• W2074967251 hasConcept C142724271 @default.
• W2074967251 hasConcept C159985019 @default.
• W2074967251 hasConcept C178790620 @default.
• W2074967251 hasConcept C185592680 @default.
• W2074967251 hasConcept C192562407 @default.
• W2074967251 hasConcept C199343813 @default.
• W2074967251 hasConcept C200990466 @default.
• W2074967251 hasConcept C2776634624 @default.
• W2074967251 hasConcept C2779409057 @default.
• W2074967251 hasConcept C2779732960 @default.
• W2074967251 hasConcept C2779820397 @default.
• W2074967251 hasConcept C2780020223 @default.
• W2074967251 hasConcept C2780100132 @default.
• W2074967251 hasConcept C2780385504 @default.
• W2074967251 hasConcept C55493867 @default.
• W2074967251 hasConcept C58747440 @default.
• W2074967251 hasConcept C71924100 @default.
• W2074967251 hasConcept C84416704 @default.
• W2074967251 hasConcept C98274493 @default.
• W2074967251 hasConceptScore W2074967251C142724271 @default.
• W2074967251 hasConceptScore W2074967251C159985019 @default.
• W2074967251 hasConceptScore W2074967251C178790620 @default.
• W2074967251 hasConceptScore W2074967251C185592680 @default.
• W2074967251 hasConceptScore W2074967251C192562407 @default.
• W2074967251 hasConceptScore W2074967251C199343813 @default.
• W2074967251 hasConceptScore W2074967251C200990466 @default.
• W2074967251 hasConceptScore W2074967251C2776634624 @default.
• W2074967251 hasConceptScore W2074967251C2779409057 @default.
• W2074967251 hasConceptScore W2074967251C2779732960 @default.
• W2074967251 hasConceptScore W2074967251C2779820397 @default.
• W2074967251 hasConceptScore W2074967251C2780020223 @default.
• W2074967251 hasConceptScore W2074967251C2780100132 @default.
• W2074967251 hasConceptScore W2074967251C2780385504 @default.
• W2074967251 hasConceptScore W2074967251C55493867 @default.
• W2074967251 hasConceptScore W2074967251C58747440 @default.
• W2074967251 hasConceptScore W2074967251C71924100 @default.
• W2074967251 hasConceptScore W2074967251C84416704 @default.
• W2074967251 hasConceptScore W2074967251C98274493 @default.
• W2074967251 hasIssue "6" @default.
• W2074967251 hasLocation W20749672511 @default.
• W2074967251 hasLocation W20749672512 @default.
• W2074967251 hasOpenAccess W2074967251 @default.
• W2074967251 hasPrimaryLocation W20749672511 @default.
• W2074967251 hasRelatedWork W2074967251 @default.
• W2074967251 hasRelatedWork W2079187070 @default.
• W2074967251 hasRelatedWork W2098879162 @default.
• W2074967251 hasRelatedWork W2101059745 @default.
• W2074967251 hasRelatedWork W2130026714 @default.
• W2074967251 hasRelatedWork W2248335811 @default.
• W2074967251 hasRelatedWork W2365176599 @default.
• W2074967251 hasRelatedWork W2556712958 @default.
• W2074967251 hasRelatedWork W3217388380 @default.

• next