FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074967466> ?p ?o ?g. }

• W2074967466 endingPage "683" @default.
• W2074967466 startingPage "679" @default.
• W2074967466 abstract "EpigenomicsVol. 3, No. 6 CommentaryCan the schizophrenia epigenome provide clues for the molecular basis of pathogenesis?Hamid M Abdolmaleky & Sam ThiagalingamHamid M AbdolmalekyDepartment of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA and Department of Genetics & Genomics, Boston University School of Medicine, Boston, MA, USA and Mental Health Research Center & Tehran Psychiatric Institute, Department of Psychiatry, Iran University of Medical Sciences, Tehran, IranSearch for more papers by this author & Sam Thiagalingam* Author for correspondenceDepartment of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA and Department of Genetics & Genomics, Boston University School of Medicine, Boston, MA, USA and Department of Pathology & Laboratory Medicine, Boston University School of Medicine, 72 East Concord Street, Boston, MA 02118, USA. Search for more papers by this authorEmail the corresponding author at samthia@bu.eduPublished Online:25 Nov 2011https://doi.org/10.2217/epi.11.94AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInRedditEmail View articleKeywords: chromatin modificationsDNA methylationepigeneticsHDACincRNAsschizophreniaReferences1 International Schizophrenia Consortium; Purcell SM, Wray NR, Stone JL et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature460(7256),748–752 (2009).Crossref, Medline, CAS, Google Scholar2 Glatt SJ, Everall IP, Kremen WS et al. Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia. Proc. Natl Acad. Sci. USA102(43),15533–15538 (2005).Crossref, Medline, CAS, Google Scholar3 Abdolmaleky HM, Cheng KH, Russo A et al. Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: a preliminary report. Am. J. Med. Genet. B Neuropsychiatr. Genet.134(1),60–66 (2005).Crossref, Google Scholar4 Grayson DR, Jia X, Chen Y et al. Reelin promoter hyper-methylation in schizophrenia. Proc. Natl Acad. Sci. USA102(26),9341–9346 (2005).Crossref, Medline, CAS, Google Scholar5 Iwamoto K, Bundo M, Yamada K et al. DNA methylation status of SOX10 correlates with its downregulation and oligodendrocyte dysfunction in schizophrenia. J. Neurosci.25(22),5376–5381 (2005).Crossref, Medline, CAS, Google Scholar6 Abdolmaleky HM, Yaqubi S, Papageorgis P et al. Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder. Schizophr. Res.129(2–3),183–190 (2011).Crossref, Medline, Google Scholar7 Tolosa A, Sanjuán J, Dagnall AM et al.FOXP2 gene and language impairment in schizophrenia: association and epigenetic studies. BMC Med. Genet.11,114, 1–8 (2010).Crossref, Medline, Google Scholar8 Abdolmaleky HM, Cheng KH, Faraone SV et al. Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder. Hum. Mol. Genet.15(21),3132–3145 (2006).Crossref, Medline, CAS, Google Scholar9 Mill J, Tang T, Kaminsky Z et al. Epigenomic profiling reveals DNA-methylation changes associated with major psychosis. Am. J. Hum. Genet.82(3),696–711 (2008).Crossref, Medline, CAS, Google Scholar10 Ghadirivasfi M, Nohesara S, Ahmadkhaniha HR et al. Hypomethylation of serotonin receptor type-2 (HTR2A) at T102C polymorphic site in DNA derived from the saliva of patients with schizophrenia and bipolar disorder. Am J. Med. Genet. B Neuropsychiatr. Genet.156(5),536–545 (2011).Crossref, CAS, Google Scholar11 Nohesara S, Ghadirivasfi M, Mostafavi S et al. DNA hypomethylation of MB-COMT promoter in the DNA derived from saliva in schizophrenia and bipolar disorder. J. Psychiatr. Res.45(11),1432–1438 (2011).Crossref, Medline, Google Scholar12 Abdolmaleky HM, Zhou JR, Thiagalingam S et al. Epigenetic and pharmacoepigenomic studies of major psychoses and potentials for therapeutics. Pharmacogenomics9(12),1809–1823 (2008).Link, CAS, Google Scholar13 Issidorides MR, Stefanis CN, Varsou E et al. Altered chromatin ultrastructure in neutrophils of schizophrenics. Nature258(5536),612–614 (1975).Crossref, Medline, CAS, Google Scholar14 Stefanis CN, Issidorides MR. Histochemical changes in the blood cells of schizophrenic patients under pimozide treatment. Biol. Psychiatry11(1),53–68 (1976).Medline, CAS, Google Scholar15 Akbarian S, Ruehl MG, Bliven E et al. Chromatin alterations associated with down-regulated metabolic gene expression in the prefrontal cortex of subjects with schizophrenia. Arch. Gen. Psychiatry62(8),829–840 (2005).Crossref, Medline, CAS, Google Scholar16 Sharma RP, Rosen C, Kartan S et al. Valproic acid and chromatin remodeling in schizophrenia and bipolar disorder: preliminary results from a clinical population. Schizophr. Res.88,227–231 (2006).Crossref, Medline, Google Scholar17 Huang HS, Matevossian A, Whittle C et al. Prefrontal dysfunction in schizophrenia involves mixed-lineage leukaemia 1-regulated histone methylation at GABAergic gene promoters. J. Neurosci.27(42),11254–11262 (2007).Crossref, Medline, CAS, Google Scholar18 Gavin DP, Rosen C, Chase K et al. Dimethylated lysine 9 of histone 3 is elevated in schizophrenia and exhibits a divergent response to histone deacetylase inhibitors in lymphocyte cultures. J. Psychiatry Neurosci.34(3),232–237 (2009).Medline, Google Scholar19 Guidotti A, Dong E, Kundakovic M et al. Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling. Trends Pharmacol. Sci.30(2),55–60 (2009).Crossref, Medline, CAS, Google Scholar20 Sharma RP, Grayson DR, Gavin DP. Histone deactylase 1 expression is increased in the prefrontal cortex of schizophrenia subjects: analysis of the National Brain Databank microarray collection. Schizophr. Res.98(1–3),111–117 (2008).Crossref, Medline, Google Scholar21 Benes FM, Lim B, Matzilevich D et al. Regulation of the GABA cell phenotype in hippocampus of schizophrenics and bipolars. Proc. Natl Acad. Sci. USA104(24),10164–10169 (2007).Crossref, Medline, CAS, Google Scholar22 Gavin DP, Kartan S, Chase K et al. Reduced baseline acetylated histone 3 levels, and a blunted response to HDAC inhibition in lymphocyte cultures from schizophrenia subjects. Schizophr. Res.103(1–3),330–332 (2008).Crossref, Medline, Google Scholar23 Santarelli DM, Beveridge NJ, Tooney PA et al. Upregulation of dicer and microRNA expression in the dorsolateral prefrontal cortex Brodmann area 46 in schizophrenia. Biol. Psychiatry69(2),180–187 (2011).Crossref, Medline, CAS, Google Scholar24 Beveridge NJ, Gardiner E, Carroll AP et al. Schizophrenia is associated with an increase in cortical microRNA biogenesis. Mol. Psychiatry15(12),1176–1189 (2010).Crossref, Medline, CAS, Google Scholar25 Beveridge NJ, Tooney PA, Carroll AP et al. Dysregulation of miRNA 181b in the temporal cortex in schizophrenia. Hum. Mol. Genet.17(8),1156–1168 (2008).Crossref, Medline, CAS, Google Scholar26 Kim AH, Reimers M, Maher B et al. MicroRNA expression profiling in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders. Schizophr. Res.124(1–3),183–191 (2010).Crossref, Medline, Google Scholar27 Zhu Y, Kalbfleisch T, Brennan MD et al. A microRNA gene is hosted in an intron of a schizophrenia-susceptibility gene. Schizophr. Res.109(1–3),86–89 (2009).Crossref, Medline, Google Scholar28 Mellios N, Galdzicka M, Ginns E et al. Gender-specific reduction of estrogen-sensitive small RNA, miR-30b, in subjects with schizophrenia. Schizophr. Bull. doi:10.1093/schbul/sbq091 (2010) (Epub ahead of print).Medline, Google Scholar29 Xu Y, Li F, Zhang B et al. MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. Schizophr. Res.119(1–3),219–227 (2010).Crossref, Medline, Google Scholar30 Moreau MP, Bruse SE, David-Rus R et al. Altered microRNA expression profiles in postmortem brain samples from individuals with schizophrenia and bipolar disorder. Biol. Psychiatry69(2),188–193 (2011).Crossref, Medline, CAS, Google ScholarFiguresReferencesRelatedDetailsCited ByDNA methyltransferase inhibitors and psychiatric disordersEZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophreniaNeurobiology of Disease, Vol. 119No association between the SNP rs1625579 in miR-137 gene and schizophrenia in Iranian populationEgyptian Journal of Medical Human Genetics, Vol. 19, No. 3HDAC1 and HDAC3 underlie dynamic H3K9 acetylation during embryonic neurogenesis and in schizophrenia‐like animals3 May 2017 | Journal of Cellular Physiology, Vol. 233, No. 1Can lncRNAs be indicators for the diagnosis of early onset or acute schizophrenia and distinguish major depressive disorder and generalized anxiety disorder?-A cross validation analysis28 March 2017 | American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Vol. 174, No. 4Long noncoding RNA as an indicator differentiating schizophrenia from major depressive disorder and generalized anxiety disorder in nonpsychiatric hospitalXuelian Cui, Wei Niu, Lingming Kong, Mingjun He, Kunhong Jiang, Shengdong Chen, Aifang Zhong, Qiaoli Zhang, Wanshuai Li, Jim Lu & Liyi Zhang16 January 2017 | Biomarkers in Medicine, Vol. 11, No. 3DNA methylation patterns of protein coding genes and long noncoding RNAs in female schizophrenic patientsEuropean Journal of Medical Genetics, Vol. 58, No. 2Events responsible for aberrant genetic and epigenetic codes in cancerDietary and environmental influences on the genomic and epigenomic codes in cancermicroRNAs as novel biomarkers of schizophrenia (Review)9 October 2014 | Experimental and Therapeutic Medicine, Vol. 8, No. 6Risk genes for schizophrenia: Translational opportunities for drug discoveryPharmacology & Therapeutics, Vol. 143, No. 1Genetic insight of schizophrenia: past and future perspectivesGene, Vol. 535, No. 2Epigenetic dysregulation of TGFβ signaling and other inflammatory genes in schizophrenia and bipolar disorderNeurology, Psychiatry and Brain Research, Vol. 20, No. 1DNA Methyltransferase Inhibitors and Psychiatric DisordersThe Dynamics of DNA Methylation in Schizophrenia and Related Psychiatric Disorders5 September 2012 | Neuropsychopharmacology, Vol. 38, No. 1DNA methylation based biomarkers: Practical considerations and applicationsBiochimie, Vol. 94, No. 11Prenatal nutrition, epigenetics and schizophrenia risk: can we test causal effects?James B Kirkbride, Ezra Susser, Marija Kundakovic, Jacob K Kresovich, George Davey Smith & Caroline L Relton12 June 2012 | Epigenomics, Vol. 4, No. 3 Vol. 3, No. 6 STAY CONNECTED Metrics Downloaded 642 times History Published online 25 November 2011 Published in print December 2011 Information© Future Medicine LtdKeywordschromatin modificationsDNA methylationepigeneticsHDACincRNAsschizophreniaFinancial & competing interests disclosureThe work carried out by HM Abdolmaleky and S Thiagalingam and discussed in this article received support from the NARSAD (The Brain & Behavior Research Foundation) independent investigator award with the designation, Dr Walter F Nicholas Investigator to S Thiagalingam. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.No writing assistance was utilized in the production of this manuscript.PDF download" @default.
• W2074967466 created "2016-06-24" @default.
• W2074967466 creator A5039698143 @default.
• W2074967466 creator A5055049097 @default.
• W2074967466 date "2011-12-01" @default.
• W2074967466 modified "2023-10-18" @default.
• W2074967466 title "Can the schizophrenia epigenome provide clues for the molecular basis of pathogenesis?" @default.
• W2074967466 cites W1964520813 @default.
• W2074967466 cites W1964850060 @default.
• W2074967466 cites W1968035201 @default.
• W2074967466 cites W1969250251 @default.
• W2074967466 cites W1983921500 @default.
• W2074967466 cites W1996758446 @default.
• W2074967466 cites W2000502968 @default.
• W2074967466 cites W2009680012 @default.
• W2074967466 cites W2013074165 @default.
• W2074967466 cites W2016441589 @default.
• W2074967466 cites W2020280030 @default.
• W2074967466 cites W2034106748 @default.
• W2074967466 cites W2045546866 @default.
• W2074967466 cites W2047958166 @default.
• W2074967466 cites W2053689957 @default.
• W2074967466 cites W2057436796 @default.
• W2074967466 cites W2066408068 @default.
• W2074967466 cites W2077061025 @default.
• W2074967466 cites W2094627293 @default.
• W2074967466 cites W2098597355 @default.
• W2074967466 cites W2117879536 @default.
• W2074967466 cites W2121471393 @default.
• W2074967466 cites W2121900484 @default.
• W2074967466 cites W2124607109 @default.
• W2074967466 cites W2125214478 @default.
• W2074967466 cites W2128025482 @default.
• W2074967466 cites W2167905519 @default.
• W2074967466 doi "https://doi.org/10.2217/epi.11.94" @default.
• W2074967466 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22126286" @default.
• W2074967466 hasPublicationYear "2011" @default.
• W2074967466 type Work @default.
• W2074967466 sameAs 2074967466 @default.
• W2074967466 citedByCount "16" @default.
• W2074967466 countsByYear W20749674662012 @default.
• W2074967466 countsByYear W20749674662014 @default.
• W2074967466 countsByYear W20749674662015 @default.
• W2074967466 countsByYear W20749674662017 @default.
• W2074967466 countsByYear W20749674662018 @default.
• W2074967466 countsByYear W20749674662021 @default.
• W2074967466 crossrefType "journal-article" @default.
• W2074967466 hasAuthorship W2074967466A5039698143 @default.
• W2074967466 hasAuthorship W2074967466A5055049097 @default.
• W2074967466 hasConcept C104317684 @default.
• W2074967466 hasConcept C117717151 @default.
• W2074967466 hasConcept C118552586 @default.
• W2074967466 hasConcept C121912465 @default.
• W2074967466 hasConcept C150194340 @default.
• W2074967466 hasConcept C179463898 @default.
• W2074967466 hasConcept C190727270 @default.
• W2074967466 hasConcept C203014093 @default.
• W2074967466 hasConcept C2776412080 @default.
• W2074967466 hasConcept C2780942790 @default.
• W2074967466 hasConcept C54355233 @default.
• W2074967466 hasConcept C60644358 @default.
• W2074967466 hasConcept C70721500 @default.
• W2074967466 hasConcept C71924100 @default.
• W2074967466 hasConcept C86803240 @default.
• W2074967466 hasConceptScore W2074967466C104317684 @default.
• W2074967466 hasConceptScore W2074967466C117717151 @default.
• W2074967466 hasConceptScore W2074967466C118552586 @default.
• W2074967466 hasConceptScore W2074967466C121912465 @default.
• W2074967466 hasConceptScore W2074967466C150194340 @default.
• W2074967466 hasConceptScore W2074967466C179463898 @default.
• W2074967466 hasConceptScore W2074967466C190727270 @default.
• W2074967466 hasConceptScore W2074967466C203014093 @default.
• W2074967466 hasConceptScore W2074967466C2776412080 @default.
• W2074967466 hasConceptScore W2074967466C2780942790 @default.
• W2074967466 hasConceptScore W2074967466C54355233 @default.
• W2074967466 hasConceptScore W2074967466C60644358 @default.
• W2074967466 hasConceptScore W2074967466C70721500 @default.
• W2074967466 hasConceptScore W2074967466C71924100 @default.
• W2074967466 hasConceptScore W2074967466C86803240 @default.
• W2074967466 hasIssue "6" @default.
• W2074967466 hasLocation W20749674661 @default.
• W2074967466 hasLocation W20749674662 @default.
• W2074967466 hasOpenAccess W2074967466 @default.
• W2074967466 hasPrimaryLocation W20749674661 @default.
• W2074967466 hasRelatedWork W1964197670 @default.
• W2074967466 hasRelatedWork W1997181459 @default.
• W2074967466 hasRelatedWork W2073587729 @default.
• W2074967466 hasRelatedWork W2093571914 @default.
• W2074967466 hasRelatedWork W2160834783 @default.
• W2074967466 hasRelatedWork W2418239907 @default.
• W2074967466 hasRelatedWork W2624965365 @default.
• W2074967466 hasRelatedWork W2883681417 @default.
• W2074967466 hasRelatedWork W3032493657 @default.
• W2074967466 hasRelatedWork W4307580626 @default.
• W2074967466 hasVolume "3" @default.
• W2074967466 isParatext "false" @default.
• W2074967466 isRetracted "false" @default.
• W2074967466 magId "2074967466" @default.

• next