Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074997802> ?p ?o ?g. }
- W2074997802 endingPage "2456" @default.
- W2074997802 startingPage "2456" @default.
- W2074997802 abstract "Irritable bowel syndrome (IBS) is one of the most common gastrointestinal disorders, characterized by abdominal pain, bloating, and changes in bowel habits. These symptoms cannot be explained by structural abnormalities and there is no specific laboratory test or biomarker for IBS. Therefore, IBS is classified as a functional disorder with diagnosis dependent on the history taking about manifested symptoms and careful physical examination. Although a great deal of research has been carried out in this area, the pathophysiology of IBS is complex and not completely understood. Multiple factors are thought to contribute to the symptoms in IBS patients; altered gastrointestinal motility, visceral hypersensitivity, and the brain-gut interaction are important classical concepts in IBS pathophysiology. New areas of research in this arena include inflammation, postinfectious low-grade inflammation, genetic and immunologic factors, an altered microbiota, dietary factors, and enteroendocrine cells. These emerging studies have not shown consistent results, provoking controversy in the IBS field. However, certain lines of evidence suggest that these mechanisms are important at least a subset of IBS patients, confirming that IBS symptoms cannot be explained by a single etiological mechanism. Therefore, it is important to keep in mind that IBS requires a more holistic approach to determining effective treatment and understanding the underlying mechanisms." @default.
- W2074997802 created "2016-06-24" @default.
- W2074997802 creator A5025597483 @default.
- W2074997802 creator A5032079722 @default.
- W2074997802 date "2014-01-01" @default.
- W2074997802 modified "2023-10-10" @default.
- W2074997802 title "Irritable bowel syndrome: Emerging paradigm in pathophysiology" @default.
- W2074997802 cites W105760296 @default.
- W2074997802 cites W1483462250 @default.
- W2074997802 cites W1527298303 @default.
- W2074997802 cites W1542508778 @default.
- W2074997802 cites W1557946895 @default.
- W2074997802 cites W1578335338 @default.
- W2074997802 cites W1583019213 @default.
- W2074997802 cites W1587016945 @default.
- W2074997802 cites W1590429307 @default.
- W2074997802 cites W1724298234 @default.
- W2074997802 cites W174461015 @default.
- W2074997802 cites W180320984 @default.
- W2074997802 cites W1898816935 @default.
- W2074997802 cites W1947293956 @default.
- W2074997802 cites W1964541944 @default.
- W2074997802 cites W1965539337 @default.
- W2074997802 cites W1966470298 @default.
- W2074997802 cites W1967848019 @default.
- W2074997802 cites W1967855220 @default.
- W2074997802 cites W1967976394 @default.
- W2074997802 cites W1968110197 @default.
- W2074997802 cites W1969660225 @default.
- W2074997802 cites W1970072701 @default.
- W2074997802 cites W1970297860 @default.
- W2074997802 cites W1970464559 @default.
- W2074997802 cites W1970813260 @default.
- W2074997802 cites W1972565216 @default.
- W2074997802 cites W1974577714 @default.
- W2074997802 cites W1975383743 @default.
- W2074997802 cites W1975622364 @default.
- W2074997802 cites W1976106554 @default.
- W2074997802 cites W1976118863 @default.
- W2074997802 cites W1976351465 @default.
- W2074997802 cites W1976522041 @default.
- W2074997802 cites W1976980195 @default.
- W2074997802 cites W1978487618 @default.
- W2074997802 cites W1979305645 @default.
- W2074997802 cites W1979871033 @default.
- W2074997802 cites W1980883408 @default.
- W2074997802 cites W1982930075 @default.
- W2074997802 cites W1983650058 @default.
- W2074997802 cites W1984598136 @default.
- W2074997802 cites W1986358628 @default.
- W2074997802 cites W1988317557 @default.
- W2074997802 cites W1991804239 @default.
- W2074997802 cites W1992676701 @default.
- W2074997802 cites W1992767714 @default.
- W2074997802 cites W1993745956 @default.
- W2074997802 cites W1994240009 @default.
- W2074997802 cites W1994933496 @default.
- W2074997802 cites W1995504800 @default.
- W2074997802 cites W1996297732 @default.
- W2074997802 cites W1997187593 @default.
- W2074997802 cites W1997901894 @default.
- W2074997802 cites W1997905904 @default.
- W2074997802 cites W2000891332 @default.
- W2074997802 cites W2001929187 @default.
- W2074997802 cites W2002562230 @default.
- W2074997802 cites W2004633453 @default.
- W2074997802 cites W2004740947 @default.
- W2074997802 cites W2004967319 @default.
- W2074997802 cites W2007005550 @default.
- W2074997802 cites W2007435811 @default.
- W2074997802 cites W2009348105 @default.
- W2074997802 cites W2013325511 @default.
- W2074997802 cites W2013943278 @default.
- W2074997802 cites W2016005958 @default.
- W2074997802 cites W2018925772 @default.
- W2074997802 cites W2021385518 @default.
- W2074997802 cites W2024601462 @default.
- W2074997802 cites W2026669688 @default.
- W2074997802 cites W2028184380 @default.
- W2074997802 cites W2028889492 @default.
- W2074997802 cites W2028890830 @default.
- W2074997802 cites W2030581107 @default.
- W2074997802 cites W2030727832 @default.
- W2074997802 cites W2031254585 @default.
- W2074997802 cites W2031805480 @default.
- W2074997802 cites W2033600566 @default.
- W2074997802 cites W2033889517 @default.
- W2074997802 cites W2037673292 @default.
- W2074997802 cites W2040475452 @default.
- W2074997802 cites W2040588098 @default.
- W2074997802 cites W2041093181 @default.
- W2074997802 cites W2042968286 @default.
- W2074997802 cites W2043676278 @default.
- W2074997802 cites W2044044822 @default.
- W2074997802 cites W2044091115 @default.
- W2074997802 cites W2045276152 @default.
- W2074997802 cites W2045998472 @default.
- W2074997802 cites W2046719673 @default.