Matches in SemOpenAlex for { <https://semopenalex.org/work/W2075102914> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2075102914 abstract "Photodynamic therapy (PDT) is a clinically approved non-invasive and curative procedure for different oncological and non-oncological applications. PDT is still under development due to several limitations which lead to partially successful photodynamic response. The crucial steps in PDT procedure are binding of the photosensitizer to outer cell membrane, its penetration and subcellular localization which envisage the target sites of reactive oxygen species generated during irradiation. Since the surrounding normal cells are also exposed to the photosensitizer and the ambient daylight can be harmful for healthy tissues after therapeutic light application, the challenging task in PDT research is to optimize the procedure in a way to reach tumor cell selectivity. The present study outlines the influence of a light exposure pre-treatment (prior therapeutic light) with specific wavelengths (365 nm and 635 nm) on the uptake, the localization and further re-localization of galactose-substituted Zn(II) phthalocyanines into MDA-MB-231 breast cancer cells. The in vitro photodynamic effect towards tumor cells was studied in comparison to the normal cell line Balb/c 3T3 (clone 31) after pre-irradiation with UV light (365 nm) and red LED (635 nm). The results suggest that the galactose functional groups of Zn(II) phthalocyanine and the harmless UV light at 365 nm favor the selective PDT response." @default.
- W2075102914 created "2016-06-24" @default.
- W2075102914 creator A5011206965 @default.
- W2075102914 creator A5014579405 @default.
- W2075102914 creator A5027629262 @default.
- W2075102914 creator A5033817074 @default.
- W2075102914 date "2013-03-15" @default.
- W2075102914 modified "2023-09-23" @default.
- W2075102914 title "Specific light exposure of galactosylated Zn(II) phthalocyanines for selective PDT effects on breast cancer cells" @default.
- W2075102914 cites W1976960072 @default.
- W2075102914 cites W1985923184 @default.
- W2075102914 cites W1991352295 @default.
- W2075102914 cites W2006051699 @default.
- W2075102914 cites W2009828713 @default.
- W2075102914 cites W2018958401 @default.
- W2075102914 cites W2037910199 @default.
- W2075102914 cites W2051469544 @default.
- W2075102914 cites W2052440805 @default.
- W2075102914 cites W2063813812 @default.
- W2075102914 cites W2070524979 @default.
- W2075102914 cites W2090749980 @default.
- W2075102914 cites W2099100426 @default.
- W2075102914 cites W2114918609 @default.
- W2075102914 cites W2131946032 @default.
- W2075102914 cites W2136248634 @default.
- W2075102914 cites W2137471638 @default.
- W2075102914 cites W2161440158 @default.
- W2075102914 cites W2170440405 @default.
- W2075102914 cites W994131379 @default.
- W2075102914 doi "https://doi.org/10.1117/12.2012013" @default.
- W2075102914 hasPublicationYear "2013" @default.
- W2075102914 type Work @default.
- W2075102914 sameAs 2075102914 @default.
- W2075102914 citedByCount "0" @default.
- W2075102914 crossrefType "proceedings-article" @default.
- W2075102914 hasAuthorship W2075102914A5011206965 @default.
- W2075102914 hasAuthorship W2075102914A5014579405 @default.
- W2075102914 hasAuthorship W2075102914A5027629262 @default.
- W2075102914 hasAuthorship W2075102914A5033817074 @default.
- W2075102914 hasConcept C111337013 @default.
- W2075102914 hasConcept C121332964 @default.
- W2075102914 hasConcept C121608353 @default.
- W2075102914 hasConcept C12554922 @default.
- W2075102914 hasConcept C126322002 @default.
- W2075102914 hasConcept C1491633281 @default.
- W2075102914 hasConcept C178790620 @default.
- W2075102914 hasConcept C185544564 @default.
- W2075102914 hasConcept C185592680 @default.
- W2075102914 hasConcept C2781323092 @default.
- W2075102914 hasConcept C2781469039 @default.
- W2075102914 hasConcept C48349386 @default.
- W2075102914 hasConcept C502942594 @default.
- W2075102914 hasConcept C530470458 @default.
- W2075102914 hasConcept C55493867 @default.
- W2075102914 hasConcept C71924100 @default.
- W2075102914 hasConcept C75473681 @default.
- W2075102914 hasConcept C86803240 @default.
- W2075102914 hasConcept C96232424 @default.
- W2075102914 hasConceptScore W2075102914C111337013 @default.
- W2075102914 hasConceptScore W2075102914C121332964 @default.
- W2075102914 hasConceptScore W2075102914C121608353 @default.
- W2075102914 hasConceptScore W2075102914C12554922 @default.
- W2075102914 hasConceptScore W2075102914C126322002 @default.
- W2075102914 hasConceptScore W2075102914C1491633281 @default.
- W2075102914 hasConceptScore W2075102914C178790620 @default.
- W2075102914 hasConceptScore W2075102914C185544564 @default.
- W2075102914 hasConceptScore W2075102914C185592680 @default.
- W2075102914 hasConceptScore W2075102914C2781323092 @default.
- W2075102914 hasConceptScore W2075102914C2781469039 @default.
- W2075102914 hasConceptScore W2075102914C48349386 @default.
- W2075102914 hasConceptScore W2075102914C502942594 @default.
- W2075102914 hasConceptScore W2075102914C530470458 @default.
- W2075102914 hasConceptScore W2075102914C55493867 @default.
- W2075102914 hasConceptScore W2075102914C71924100 @default.
- W2075102914 hasConceptScore W2075102914C75473681 @default.
- W2075102914 hasConceptScore W2075102914C86803240 @default.
- W2075102914 hasConceptScore W2075102914C96232424 @default.
- W2075102914 hasLocation W20751029141 @default.
- W2075102914 hasOpenAccess W2075102914 @default.
- W2075102914 hasPrimaryLocation W20751029141 @default.
- W2075102914 hasRelatedWork W2547917240 @default.
- W2075102914 hasRelatedWork W2611800801 @default.
- W2075102914 hasRelatedWork W2755085798 @default.
- W2075102914 hasRelatedWork W2765767823 @default.
- W2075102914 hasRelatedWork W2904739955 @default.
- W2075102914 hasRelatedWork W4226468165 @default.
- W2075102914 hasRelatedWork W4243466585 @default.
- W2075102914 hasRelatedWork W4306850889 @default.
- W2075102914 hasRelatedWork W4312452148 @default.
- W2075102914 hasRelatedWork W4313242153 @default.
- W2075102914 isParatext "false" @default.
- W2075102914 isRetracted "false" @default.
- W2075102914 magId "2075102914" @default.
- W2075102914 workType "article" @default.