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• W2075117921 abstract "The transactivation potential of Nm23‐H1, a homolog of c‐myc transcription factor Nm23‐H2/PuF was assessed in yeast as a fusion protein with the DNA binding domains (DBDs) of GAL4 and LexA. The C‐terminal half of Nm23‐H1 exhibited strong transactivation of the reporter genes, LacZ and Leu2 carrying GAL4 and LexA upstream activating sequences (UASs), whereas the full‐length Nm23‐H1 and its N‐terminal did not. Similar results were also obtained with Nm23‐H2/PuF transactivating the reporter genes only by the C‐terminus fused to GAL4 and LexA DBDs. Hence, our results suggested a possible regulatory role of the N‐termini of Nm23 isotypes upon transactivation." @default.
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• W2075117921 date "1998-02-20" @default.
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• W2075117921 title "Transactivation potential of the C-terminus of human Nm23-H1" @default.
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• W2075117921 doi "https://doi.org/10.1016/s0014-5793(98)00100-8" @default.
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