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- W2075155473 abstract "Sodium salicylate and to a lesser extent acetylsalicylic acid both inhibit the activity of cyclic 3′,5′-AMP-dependent protein kinase measured by the phosphorylation of histone. The competitive type of inhibition is only seen in the presence of cyclic 3′,5′-AMP. In the absence of cyclic 3′,5′-AMP the unstimulated activity of protein kinase is increased. The impairment of function of protein kinase correlates with the previously reported inhibition of binding of cyclic 3′,5′-AMP to cyclic 3′, 5′-AMP-dependent protein kinase and indicates that the action of sodium salicylate may involve the “regulatory site” of the protein kinase." @default.
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- W2075155473 date "1973-09-01" @default.
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- W2075155473 title "Effects of sodium salicylate and acetylsalicylic acid on cyclic 3′,5′-amp-dependent protein kinase" @default.
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- W2075155473 doi "https://doi.org/10.1016/0006-2952(73)90002-6" @default.
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