FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2075159143> ?p ?o ?g. }

• W2075159143 endingPage "681" @default.
• W2075159143 startingPage "679" @default.
• W2075159143 abstract "Laube et al from The Johns Hopkins Medical Institutions have a history of studying mucociliary clearance in vivo in children with cystic fibrosis (CF). In this issue of The Journal, the authors generated the hypothesis that mucus removal is impaired in children with CF who have been recently infected with Pseudomonas aeruginosa. To investigate this question, they compared mucociliary clearance, cough clearance, and forced expiratory volume in 1 second (FEV1) in children with CF and mild lung disease. The group was divided into those who were P aeruginosa negative and those who were P aeruginosa positive. The study was performed using gamma camera imaging of the right lung, following inhalation of 99m technetium sulfur-colloid. The results show that although there were no differences between the groups in mucociliary clearance in 60 minutes, mucociliary clearance in 24 hours, mean computed tomography (CT) scores, or FEV1, the total mucociliary clearance was significantly decreased in P aeruginosa positive children at 90 minutes. In addition, there were negative correlations between mucociliary clearance and total lung CT scores. They conclude that infection with P aeruginosa is associated with a significant slowing of mucociliary clearance in children with mild CF and that it might be a more sensitive indicator than measurements of FEV1.Article page 839▶ Laube et al from The Johns Hopkins Medical Institutions have a history of studying mucociliary clearance in vivo in children with cystic fibrosis (CF). In this issue of The Journal, the authors generated the hypothesis that mucus removal is impaired in children with CF who have been recently infected with Pseudomonas aeruginosa. To investigate this question, they compared mucociliary clearance, cough clearance, and forced expiratory volume in 1 second (FEV1) in children with CF and mild lung disease. The group was divided into those who were P aeruginosa negative and those who were P aeruginosa positive. The study was performed using gamma camera imaging of the right lung, following inhalation of 99m technetium sulfur-colloid. The results show that although there were no differences between the groups in mucociliary clearance in 60 minutes, mucociliary clearance in 24 hours, mean computed tomography (CT) scores, or FEV1, the total mucociliary clearance was significantly decreased in P aeruginosa positive children at 90 minutes. In addition, there were negative correlations between mucociliary clearance and total lung CT scores. They conclude that infection with P aeruginosa is associated with a significant slowing of mucociliary clearance in children with mild CF and that it might be a more sensitive indicator than measurements of FEV1. Article page 839▶ Mucus Removal Is Impaired in Children with Cystic Fibrosis Who Have Been Infected by Pseudomonas aeruginosaThe Journal of PediatricsVol. 164Issue 4PreviewTo determine if mucus removal is impaired in children with cystic fibrosis (CF) who have been recently infected with Pseudomonas aeruginosa. Full-Text PDF" @default.
• W2075159143 created "2016-06-24" @default.
• W2075159143 creator A5065014622 @default.
• W2075159143 date "2014-04-01" @default.
• W2075159143 modified "2023-10-16" @default.
• W2075159143 title "Impaired mucociliary clearance in cystic fibrosis and P aeruginosa" @default.
• W2075159143 doi "https://doi.org/10.1016/j.jpeds.2014.02.010" @default.
• W2075159143 hasPublicationYear "2014" @default.
• W2075159143 type Work @default.
• W2075159143 sameAs 2075159143 @default.
• W2075159143 citedByCount "2" @default.
• W2075159143 countsByYear W20751591432022 @default.
• W2075159143 crossrefType "journal-article" @default.
• W2075159143 hasAuthorship W2075159143A5065014622 @default.
• W2075159143 hasConcept C114682108 @default.
• W2075159143 hasConcept C126322002 @default.
• W2075159143 hasConcept C142724271 @default.
• W2075159143 hasConcept C18206936 @default.
• W2075159143 hasConcept C18903297 @default.
• W2075159143 hasConcept C2776938444 @default.
• W2075159143 hasConcept C2776954882 @default.
• W2075159143 hasConcept C2777312293 @default.
• W2075159143 hasConcept C2777637488 @default.
• W2075159143 hasConcept C2777714996 @default.
• W2075159143 hasConcept C42219234 @default.
• W2075159143 hasConcept C523546767 @default.
• W2075159143 hasConcept C54355233 @default.
• W2075159143 hasConcept C71924100 @default.
• W2075159143 hasConcept C86803240 @default.
• W2075159143 hasConcept C90924648 @default.
• W2075159143 hasConceptScore W2075159143C114682108 @default.
• W2075159143 hasConceptScore W2075159143C126322002 @default.
• W2075159143 hasConceptScore W2075159143C142724271 @default.
• W2075159143 hasConceptScore W2075159143C18206936 @default.
• W2075159143 hasConceptScore W2075159143C18903297 @default.
• W2075159143 hasConceptScore W2075159143C2776938444 @default.
• W2075159143 hasConceptScore W2075159143C2776954882 @default.
• W2075159143 hasConceptScore W2075159143C2777312293 @default.
• W2075159143 hasConceptScore W2075159143C2777637488 @default.
• W2075159143 hasConceptScore W2075159143C2777714996 @default.
• W2075159143 hasConceptScore W2075159143C42219234 @default.
• W2075159143 hasConceptScore W2075159143C523546767 @default.
• W2075159143 hasConceptScore W2075159143C54355233 @default.
• W2075159143 hasConceptScore W2075159143C71924100 @default.
• W2075159143 hasConceptScore W2075159143C86803240 @default.
• W2075159143 hasConceptScore W2075159143C90924648 @default.
• W2075159143 hasIssue "4" @default.
• W2075159143 hasLocation W20751591431 @default.
• W2075159143 hasOpenAccess W2075159143 @default.
• W2075159143 hasPrimaryLocation W20751591431 @default.
• W2075159143 hasRelatedWork W1496289295 @default.
• W2075159143 hasRelatedWork W2064683630 @default.
• W2075159143 hasRelatedWork W2129407773 @default.
• W2075159143 hasRelatedWork W2891635994 @default.
• W2075159143 hasRelatedWork W2902345658 @default.
• W2075159143 hasRelatedWork W3029252633 @default.
• W2075159143 hasRelatedWork W3035813324 @default.
• W2075159143 hasRelatedWork W4220966082 @default.
• W2075159143 hasRelatedWork W4281836312 @default.
• W2075159143 hasRelatedWork W561770421 @default.
• W2075159143 hasVolume "164" @default.
• W2075159143 isParatext "false" @default.
• W2075159143 isRetracted "false" @default.
• W2075159143 magId "2075159143" @default.
• W2075159143 workType "article" @default.