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• W2075242479 abstract "Mesoscopic fluorescence molecular tomography (MFMT) is new imaging modality aiming at 3-D imaging of molecular probes in a few millimeter thick biological samples with high-spatial resolution. In this paper, we develop a compressive sensing-based reconstruction method with l1-norm regularization for MFMT with the goal of improving spatial resolution and stability of the optical inverse problem. Three-dimensional numerical simulations of anatomically accurate microvasculature and real data obtained from phantom experiments are employed to evaluate the merits of the proposed method. Experimental results show that the proposed method can achieve 80 μm spatial resolution for a biological sample of 3 mm thickness and more accurate quantifications of concentrations and locations for the fluorophore distribution than those of the conventional methods." @default.
• W2075242479 created "2016-06-24" @default.
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• W2075242479 date "2015-01-01" @default.
• W2075242479 modified "2023-10-12" @default.
• W2075242479 title "High-Resolution Mesoscopic Fluorescence Molecular Tomography Based on Compressive Sensing" @default.
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• W2075242479 doi "https://doi.org/10.1109/tbme.2014.2347284" @default.
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