FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2075302326> ?p ?o ?g. }

• W2075302326 endingPage "31" @default.
• W2075302326 startingPage "17" @default.
• W2075302326 abstract "Feline calicivirus (FCV) is characterised by a high degree of antigenic variation potentially compromising vaccine efficacy. Inclusion of several FCV strains or antigens in current vaccines could be a means to improve protection against antigenically distinct isolates. This study evaluated the synergy between two FCV strains (FCVG1 and FCV431) by comparing immunity induced by either strain with that provided by a combination of the two strains against an heterologous challenge with antigenically distant FCV strains (FCV393 and FCV220). Thirty-two SPF kittens were randomly allocated to four groups of eight cats in each group. Groups B, C and D cats were vaccinated once subcutaneously with strains FCVG1, FCV431, and FCVG1 + FCV431, respectively. Each kitten received a total dose of 10(3.4) CCID50 of FCV. Control group A was not immunised. On day 31, four cats from each group were challenged oronasally with FCV220 and four cats with FCV393. Following challenge, the cats were monitored for clinical signs, viral shedding and antibody responses. FCV220 and FCV393 induced severe clinical signs in control cats typical of FCV infection. Immunisation with both strains mixed together induced higher neutralizing antibody titres against FCV220 and FCV393 strains on average. Protection was observed in all groups, however combination of the two strains resulted in a better clinical protection and reduction of virus shedding after heterologous challenge. A moderate correlation was observed between neutralizing antibody titres at the time of challenge and protection against clinical signs. These results indicated that vaccines combining antigens from different FCV strains may induce a broader heterologous protection." @default.
• W2075302326 created "2016-06-24" @default.
• W2075302326 creator A5002908636 @default.
• W2075302326 creator A5055870060 @default.
• W2075302326 creator A5074491270 @default.
• W2075302326 creator A5088674104 @default.
• W2075302326 date "2005-03-01" @default.
• W2075302326 modified "2023-10-13" @default.
• W2075302326 title "Immunisation with a combination of two complementary feline calicivirus strains induces a broad cross-protection against heterologous challenges" @default.
• W2075302326 cites W1764747117 @default.
• W2075302326 cites W1874177544 @default.
• W2075302326 cites W1907092169 @default.
• W2075302326 cites W1969450334 @default.
• W2075302326 cites W1970606914 @default.
• W2075302326 cites W1971440714 @default.
• W2075302326 cites W1976496356 @default.
• W2075302326 cites W1976739071 @default.
• W2075302326 cites W1980186536 @default.
• W2075302326 cites W1985696838 @default.
• W2075302326 cites W2000043834 @default.
• W2075302326 cites W2022673339 @default.
• W2075302326 cites W2023117071 @default.
• W2075302326 cites W2032375324 @default.
• W2075302326 cites W2034038520 @default.
• W2075302326 cites W2057519757 @default.
• W2075302326 cites W2057724949 @default.
• W2075302326 cites W2058656812 @default.
• W2075302326 cites W2060082753 @default.
• W2075302326 cites W2070748268 @default.
• W2075302326 cites W2075539332 @default.
• W2075302326 cites W2076258503 @default.
• W2075302326 cites W2082722410 @default.
• W2075302326 cites W2109633532 @default.
• W2075302326 cites W2121182046 @default.
• W2075302326 cites W2135906189 @default.
• W2075302326 cites W2136166839 @default.
• W2075302326 cites W2138270253 @default.
• W2075302326 cites W2140546048 @default.
• W2075302326 cites W2148439197 @default.
• W2075302326 cites W2165842933 @default.
• W2075302326 cites W2183736964 @default.
• W2075302326 cites W4255142662 @default.
• W2075302326 cites W53702561 @default.
• W2075302326 doi "https://doi.org/10.1016/j.vetmic.2004.12.010" @default.
• W2075302326 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15737470" @default.
• W2075302326 hasPublicationYear "2005" @default.
• W2075302326 type Work @default.
• W2075302326 sameAs 2075302326 @default.
• W2075302326 citedByCount "38" @default.
• W2075302326 countsByYear W20753023262012 @default.
• W2075302326 countsByYear W20753023262013 @default.
• W2075302326 countsByYear W20753023262014 @default.
• W2075302326 countsByYear W20753023262015 @default.
• W2075302326 countsByYear W20753023262016 @default.
• W2075302326 countsByYear W20753023262017 @default.
• W2075302326 countsByYear W20753023262019 @default.
• W2075302326 countsByYear W20753023262021 @default.
• W2075302326 countsByYear W20753023262022 @default.
• W2075302326 crossrefType "journal-article" @default.
• W2075302326 hasAuthorship W2075302326A5002908636 @default.
• W2075302326 hasAuthorship W2075302326A5055870060 @default.
• W2075302326 hasAuthorship W2075302326A5074491270 @default.
• W2075302326 hasAuthorship W2075302326A5088674104 @default.
• W2075302326 hasConcept C104317684 @default.
• W2075302326 hasConcept C126322002 @default.
• W2075302326 hasConcept C12914427 @default.
• W2075302326 hasConcept C147483822 @default.
• W2075302326 hasConcept C159047783 @default.
• W2075302326 hasConcept C159654299 @default.
• W2075302326 hasConcept C203014093 @default.
• W2075302326 hasConcept C2522874641 @default.
• W2075302326 hasConcept C2777747160 @default.
• W2075302326 hasConcept C2778749613 @default.
• W2075302326 hasConcept C2779261636 @default.
• W2075302326 hasConcept C2779341262 @default.
• W2075302326 hasConcept C2779904517 @default.
• W2075302326 hasConcept C2780115692 @default.
• W2075302326 hasConcept C2780727368 @default.
• W2075302326 hasConcept C2780980013 @default.
• W2075302326 hasConcept C3018913218 @default.
• W2075302326 hasConcept C55493867 @default.
• W2075302326 hasConcept C71924100 @default.
• W2075302326 hasConcept C86803240 @default.
• W2075302326 hasConcept C8891405 @default.
• W2075302326 hasConcept C89423630 @default.
• W2075302326 hasConceptScore W2075302326C104317684 @default.
• W2075302326 hasConceptScore W2075302326C126322002 @default.
• W2075302326 hasConceptScore W2075302326C12914427 @default.
• W2075302326 hasConceptScore W2075302326C147483822 @default.
• W2075302326 hasConceptScore W2075302326C159047783 @default.
• W2075302326 hasConceptScore W2075302326C159654299 @default.
• W2075302326 hasConceptScore W2075302326C203014093 @default.
• W2075302326 hasConceptScore W2075302326C2522874641 @default.
• W2075302326 hasConceptScore W2075302326C2777747160 @default.
• W2075302326 hasConceptScore W2075302326C2778749613 @default.
• W2075302326 hasConceptScore W2075302326C2779261636 @default.
• W2075302326 hasConceptScore W2075302326C2779341262 @default.
• W2075302326 hasConceptScore W2075302326C2779904517 @default.

• next