FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2075314580> ?p ?o ?g. }

• W2075314580 endingPage "738" @default.
• W2075314580 startingPage "733" @default.
• W2075314580 abstract "We evaluated the effect of the point mutation of guanine to thymine at nucleotide position 894 (G894T) of the endothelial nitric oxide synthase (eNOS) gene on inflammatory and oxidative stress markers.We studied genetic information from 270 men (18-87 years old) and 325 women (18-89 years old). Participants without any clinical evidence of cardiovascular or other atherosclerotic disease were randomly selected from the general population according to the age-sex distribution of Athens greater area. Genomic DNA was extracted from 2 to 5 mL of fresh or frozen whole blood using standard methods.The DNA analysis showed that 10.6% of the participants were Asp-homozygotes (Asp/Asp), 40% heterozygotes (Asp/Glu) and 49.4% Glu-homozygotes (Glu/Glu). Compared to Asp/Glu and Glu/Glu, Asp/Asp had higher levels of fibrinogen (332 +/- 46 or 329 +/- 33 vs 319 +/- 29 mg/dL, P =.029), white blood cells (6.9 +/- 0.6 or 6.5 +/- 0.3 vs 6.1 +/- 0.9 x 10(3) counts, P =.044), and oxidized low-density lipoprotein cholesterol (68 +/- 21 or 61 +/- 22 vs 59 +/- 20 mg/dL, P =.039), after controlling for several potential confounders. An insignificant association was found between homocysteine (P =.08), C-reactive protein (P =.096), and the distribution of G894T polymorphism (P <.1). No association between the distribution of the polymorphism and hypertension status of the participants was observed.Our results imply that G894T polymorphism of the endothelial nitric oxide synthase gene is associated with elevated levels of inflammatory and oxidative stress markers, which may partially explain the increased prevalence of G894T polymorphism among patients with cardiovascular disease." @default.
• W2075314580 created "2016-06-24" @default.
• W2075314580 creator A5005228083 @default.
• W2075314580 creator A5007720638 @default.
• W2075314580 creator A5021307214 @default.
• W2075314580 creator A5021398096 @default.
• W2075314580 creator A5026204973 @default.
• W2075314580 creator A5036030334 @default.
• W2075314580 creator A5085496501 @default.
• W2075314580 date "2004-10-01" @default.
• W2075314580 modified "2023-09-30" @default.
• W2075314580 title "Evidence for association between endothelial nitric oxide synthase gene polymorphism (G894T) and inflammatory markers: The ATTICA study" @default.
• W2075314580 cites W1969255480 @default.
• W2075314580 cites W1994640204 @default.
• W2075314580 cites W2002921189 @default.
• W2075314580 cites W2006705030 @default.
• W2075314580 cites W2011846765 @default.
• W2075314580 cites W2016054237 @default.
• W2075314580 cites W2018227915 @default.
• W2075314580 cites W2040901946 @default.
• W2075314580 cites W2045138089 @default.
• W2075314580 cites W2048849415 @default.
• W2075314580 cites W2066010552 @default.
• W2075314580 cites W2081221323 @default.
• W2075314580 cites W2084124265 @default.
• W2075314580 cites W2084398452 @default.
• W2075314580 cites W2086204563 @default.
• W2075314580 cites W2098903228 @default.
• W2075314580 cites W2102440403 @default.
• W2075314580 cites W2104391287 @default.
• W2075314580 cites W2120991542 @default.
• W2075314580 cites W2122479313 @default.
• W2075314580 cites W2132634618 @default.
• W2075314580 cites W2138956360 @default.
• W2075314580 cites W2140068354 @default.
• W2075314580 cites W2141719916 @default.
• W2075314580 cites W2148174695 @default.
• W2075314580 cites W2319460905 @default.
• W2075314580 cites W41201517 @default.
• W2075314580 cites W4239027098 @default.
• W2075314580 cites W4294183730 @default.
• W2075314580 doi "https://doi.org/10.1016/j.ahj.2004.04.022" @default.
• W2075314580 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15459608" @default.
• W2075314580 hasPublicationYear "2004" @default.
• W2075314580 type Work @default.
• W2075314580 sameAs 2075314580 @default.
• W2075314580 citedByCount "37" @default.
• W2075314580 countsByYear W20753145802012 @default.
• W2075314580 countsByYear W20753145802013 @default.
• W2075314580 countsByYear W20753145802014 @default.
• W2075314580 countsByYear W20753145802015 @default.
• W2075314580 countsByYear W20753145802018 @default.
• W2075314580 countsByYear W20753145802019 @default.
• W2075314580 countsByYear W20753145802020 @default.
• W2075314580 countsByYear W20753145802022 @default.
• W2075314580 countsByYear W20753145802023 @default.
• W2075314580 crossrefType "journal-article" @default.
• W2075314580 hasAuthorship W2075314580A5005228083 @default.
• W2075314580 hasAuthorship W2075314580A5007720638 @default.
• W2075314580 hasAuthorship W2075314580A5021307214 @default.
• W2075314580 hasAuthorship W2075314580A5021398096 @default.
• W2075314580 hasAuthorship W2075314580A5026204973 @default.
• W2075314580 hasAuthorship W2075314580A5036030334 @default.
• W2075314580 hasAuthorship W2075314580A5085496501 @default.
• W2075314580 hasConcept C104317684 @default.
• W2075314580 hasConcept C126322002 @default.
• W2075314580 hasConcept C134018914 @default.
• W2075314580 hasConcept C135763542 @default.
• W2075314580 hasConcept C2776151105 @default.
• W2075314580 hasConcept C2777090595 @default.
• W2075314580 hasConcept C2777622882 @default.
• W2075314580 hasConcept C519581460 @default.
• W2075314580 hasConcept C54355233 @default.
• W2075314580 hasConcept C71924100 @default.
• W2075314580 hasConcept C86803240 @default.
• W2075314580 hasConceptScore W2075314580C104317684 @default.
• W2075314580 hasConceptScore W2075314580C126322002 @default.
• W2075314580 hasConceptScore W2075314580C134018914 @default.
• W2075314580 hasConceptScore W2075314580C135763542 @default.
• W2075314580 hasConceptScore W2075314580C2776151105 @default.
• W2075314580 hasConceptScore W2075314580C2777090595 @default.
• W2075314580 hasConceptScore W2075314580C2777622882 @default.
• W2075314580 hasConceptScore W2075314580C519581460 @default.
• W2075314580 hasConceptScore W2075314580C54355233 @default.
• W2075314580 hasConceptScore W2075314580C71924100 @default.
• W2075314580 hasConceptScore W2075314580C86803240 @default.
• W2075314580 hasIssue "4" @default.
• W2075314580 hasLocation W20753145801 @default.
• W2075314580 hasLocation W20753145802 @default.
• W2075314580 hasOpenAccess W2075314580 @default.
• W2075314580 hasPrimaryLocation W20753145801 @default.
• W2075314580 hasRelatedWork W1623258072 @default.
• W2075314580 hasRelatedWork W1972190589 @default.
• W2075314580 hasRelatedWork W2008087125 @default.
• W2075314580 hasRelatedWork W2054818626 @default.
• W2075314580 hasRelatedWork W2057533703 @default.
• W2075314580 hasRelatedWork W2087337247 @default.
• W2075314580 hasRelatedWork W2089295326 @default.

• next