Matches in SemOpenAlex for { <https://semopenalex.org/work/W2075318449> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2075318449 endingPage "318" @default.
- W2075318449 startingPage "301" @default.
- W2075318449 abstract "Inactivation ofBacillus subtilis orf1177 in an otherwise Rec+strain reduced genetic exchange and DNA repair. When the mutation was transferred into a set of recombination-deficient and repair-deficient strains, the DNA repair and recombination ability of the double or triple mutant strains was drastically reduced.B. subtilisOrf1177 protein shares substantial homology with theEscherichia coliMfd, RecG and UvrB proteins.In vivoanalysis of UV-induced mutations suggests that Orf1177 is necessary for strand- specific DNA repair, as is the case for theE. coliMfd protein. Therefore,orf1177 and Orf1177 were termedmfdgene and Mfd protein, respectively. The purified Mfd protein has a native molecular mass of 140 kDa (expected molecular mass 133 kDa). The Mfd protein is a sequence-independent DNA binding protein with weak ATPase activity. The Mfd protein was able to displacein vitro B. subtilisorE. coliRNA polymerase stalled at a lesion. Therefore, Mfd protein appears to target the transcribed strand for repair by recognizing a stalled RNA polymerase and dissociating it from the DNA. In addition, the strong recombination-deficient phenotype ofmfd−rec−strains suggests that Mfd protein is involved in homologous DNA recombination." @default.
- W2075318449 created "2016-06-24" @default.
- W2075318449 creator A5007078528 @default.
- W2075318449 creator A5011019685 @default.
- W2075318449 creator A5038388661 @default.
- W2075318449 creator A5042605591 @default.
- W2075318449 creator A5077615756 @default.
- W2075318449 date "1996-02-01" @default.
- W2075318449 modified "2023-10-15" @default.
- W2075318449 title "The Mfd Protein ofBacillus subtilis168 is Involved in both Transcription-coupled DNA Repair and DNA Recombination" @default.
- W2075318449 doi "https://doi.org/10.1006/jmbi.1996.0087" @default.
- W2075318449 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8594198" @default.
- W2075318449 hasPublicationYear "1996" @default.
- W2075318449 type Work @default.
- W2075318449 sameAs 2075318449 @default.
- W2075318449 citedByCount "69" @default.
- W2075318449 countsByYear W20753184492012 @default.
- W2075318449 countsByYear W20753184492013 @default.
- W2075318449 countsByYear W20753184492014 @default.
- W2075318449 countsByYear W20753184492015 @default.
- W2075318449 countsByYear W20753184492016 @default.
- W2075318449 countsByYear W20753184492017 @default.
- W2075318449 countsByYear W20753184492018 @default.
- W2075318449 countsByYear W20753184492020 @default.
- W2075318449 countsByYear W20753184492021 @default.
- W2075318449 countsByYear W20753184492022 @default.
- W2075318449 countsByYear W20753184492023 @default.
- W2075318449 crossrefType "journal-article" @default.
- W2075318449 hasAuthorship W2075318449A5007078528 @default.
- W2075318449 hasAuthorship W2075318449A5011019685 @default.
- W2075318449 hasAuthorship W2075318449A5038388661 @default.
- W2075318449 hasAuthorship W2075318449A5042605591 @default.
- W2075318449 hasAuthorship W2075318449A5077615756 @default.
- W2075318449 hasConcept C102744134 @default.
- W2075318449 hasConcept C104317684 @default.
- W2075318449 hasConcept C113271649 @default.
- W2075318449 hasConcept C134935766 @default.
- W2075318449 hasConcept C153911025 @default.
- W2075318449 hasConcept C2756471 @default.
- W2075318449 hasConcept C54355233 @default.
- W2075318449 hasConcept C552990157 @default.
- W2075318449 hasConcept C86339819 @default.
- W2075318449 hasConcept C86803240 @default.
- W2075318449 hasConcept C94966510 @default.
- W2075318449 hasConceptScore W2075318449C102744134 @default.
- W2075318449 hasConceptScore W2075318449C104317684 @default.
- W2075318449 hasConceptScore W2075318449C113271649 @default.
- W2075318449 hasConceptScore W2075318449C134935766 @default.
- W2075318449 hasConceptScore W2075318449C153911025 @default.
- W2075318449 hasConceptScore W2075318449C2756471 @default.
- W2075318449 hasConceptScore W2075318449C54355233 @default.
- W2075318449 hasConceptScore W2075318449C552990157 @default.
- W2075318449 hasConceptScore W2075318449C86339819 @default.
- W2075318449 hasConceptScore W2075318449C86803240 @default.
- W2075318449 hasConceptScore W2075318449C94966510 @default.
- W2075318449 hasIssue "2" @default.
- W2075318449 hasLocation W20753184491 @default.
- W2075318449 hasLocation W20753184492 @default.
- W2075318449 hasOpenAccess W2075318449 @default.
- W2075318449 hasPrimaryLocation W20753184491 @default.
- W2075318449 hasRelatedWork W1569837138 @default.
- W2075318449 hasRelatedWork W1780609825 @default.
- W2075318449 hasRelatedWork W1970445060 @default.
- W2075318449 hasRelatedWork W2136145320 @default.
- W2075318449 hasRelatedWork W2137627491 @default.
- W2075318449 hasRelatedWork W2401497319 @default.
- W2075318449 hasRelatedWork W2775365400 @default.
- W2075318449 hasRelatedWork W4256104864 @default.
- W2075318449 hasRelatedWork W4381295070 @default.
- W2075318449 hasRelatedWork W45614681 @default.
- W2075318449 hasVolume "256" @default.
- W2075318449 isParatext "false" @default.
- W2075318449 isRetracted "false" @default.
- W2075318449 magId "2075318449" @default.
- W2075318449 workType "article" @default.