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- W2075344430 abstract "To study the role of IL-5 in allergic airway hyperreactivity, the time course for the production of cytokines, the infiltration of inflammatory cells and the onset of airway hyperreactivity after three inhalations of antigens were studied in mice. The effect of the soluble α-chain of murine recombinant interleukin-5 receptor (sIL-5Rα) on these phenomena was also examined. Whereas IL-5 and IL-4 were produced in significant amounts, IL-1, IL-2 and γ-interferon (γ-IFN) were not detected even after three antigen inhalations. Monocytes and eosinophils but not neutrophils increased significantly after the third antigen exposure. The airway responsiveness to acetylcholine increased after the third aeroantigen-challenge. sIL-5Rα, administered after each antigen-challenge, suppressed BAL eosinophilia with little effect on airway hyperreactivity." @default.
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- W2075344430 date "2006-06-01" @default.
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- W2075344430 title "Quantitative evaluation of the time course of effects of acute ethanol on PolyI:C induced production of cytokines, chemokines, and corticosterone" @default.
- W2075344430 doi "https://doi.org/10.1016/j.alcohol.2006.09.015" @default.
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