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- W2075366973 abstract "This article reviews the current status of surgical treatment of epilepsy and introduces the ongoing challenges. Seizure outcome of resective surgery for focal seizures associated with focal lesions is satisfactory. Particularly for mesial temporal lobe epilepsy, surgical treatment should be considered from the earlier stage of the disease. Meanwhile, surgical outcome in nonlesional extratemporal lobe epilepsy is still to be improved using various approaches. Disconnective surgeries reduce surgical complications of extensive resections while achieving equivalent or better seizure outcomes. Multiple subpial transection is still being modified expecting a better outcome by transection to the vertical cortices along the sulci- and multi-directional transection from a single entry point. Hippocampal transection is expected to preserve memory function while interrupting the abnormal epileptic synchronization. Proper selection or combination of subdural and depth electrodes and a wide-band analysis of electroencephalography may improve the accurate localization of epileptogenic region. Patients for whom curative resective surgery is not indicated because of generalized or bilateral multiple nature of their epilepsies, neuromodulation therapies are options of treatment which palliate their seizures." @default.
- W2075366973 created "2016-06-24" @default.
- W2075366973 creator A5012443421 @default.
- W2075366973 date "2015-01-01" @default.
- W2075366973 modified "2023-10-03" @default.
- W2075366973 title "Epilepsy Surgery: Current Status and Ongoing Challenges" @default.
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- W2075366973 doi "https://doi.org/10.2176/nmc.ra.2014-0414" @default.
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