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- W2075386760 abstract "The rates of NADH oxidation during the hydroxylation of camphor by cytochrome P‐450 cam were followed in the presence of co‐solvents used to increase the osmotic pressure surrounding the protein‐bound water. As a result, the measured V max decreases independently of the perturbant tested. Roughly 28 molecules of water, involved during the catalytic cycle, are deduced from the variation of V max as a function of osmotic pressure. These molecules, in part, could be those present in the cytochrome P.450 cam ‐putidaredoxin interface." @default.
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- W2075386760 date "1992-11-09" @default.
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- W2075386760 title "A critical role of protein-bound water in the catalytic cycle of cytochrome P-450 camphor" @default.
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- W2075386760 doi "https://doi.org/10.1016/0014-5793(92)80946-e" @default.
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