FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2075417967> ?p ?o ?g. }

• W2075417967 endingPage "950" @default.
• W2075417967 startingPage "941" @default.
• W2075417967 abstract "We aimed to identify risk factors for recurrent syncope in children and adolescents with congenital long QT syndrome (LQTS).Data regarding risk assessment in LQTS after the occurrence of the first syncope episode are limited.The Prentice-Williams-Peterson conditional gap time model was used to identify risk factors for recurrent syncope from birth through age 20 years among 1,648 patients from the International Long QT Syndrome Registry.Multivariate analysis demonstrated that corrected QT interval (QTc) duration (≥500 ms) was a significant predictor of a first syncope episode (hazard ratio: 2.16), whereas QTc effect was attenuated when the end points of the second, third, and fourth syncope episodes were evaluated (hazard ratios: 1.29, 0.99, 0.90, respectively; p < 0.001 for the null hypothesis that all 4 hazard ratios are identical). A genotype-specific subanalysis showed that during childhood (0 to 12 years), males with LQTS type 1 had the highest rate of a first syncope episode (p = 0.001) but exhibited similar rates of subsequent events as other genotype-sex subsets (p = 0.63). In contrast, in the age range of 13 to 20 years, long QT syndrome type 2 females experienced the highest rate of both first and subsequent syncope events (p < 0.001 and p = 0.01, respectively). Patients who experienced ≥1 episodes of syncope had a 6- to 12-fold (p < 0.001 for all) increase in the risk of subsequent fatal/near-fatal events independently of QTc duration. Beta-blocker therapy was associated with a significant reduction in the risk of recurrent syncope and subsequent fatal/near-fatal events.Children and adolescents who present after an episode of syncope should be considered to be at a high risk of the development of subsequent syncope episodes and fatal/near-fatal events regardless of QTc duration." @default.
• W2075417967 created "2016-06-24" @default.
• W2075417967 creator A5001410007 @default.
• W2075417967 creator A5002121570 @default.
• W2075417967 creator A5008966758 @default.
• W2075417967 creator A5010388094 @default.
• W2075417967 creator A5012507741 @default.
• W2075417967 creator A5021196395 @default.
• W2075417967 creator A5025486359 @default.
• W2075417967 creator A5038126690 @default.
• W2075417967 creator A5049150501 @default.
• W2075417967 creator A5055125250 @default.
• W2075417967 creator A5057507865 @default.
• W2075417967 creator A5059052503 @default.
• W2075417967 creator A5066716873 @default.
• W2075417967 creator A5075060212 @default.
• W2075417967 creator A5076422519 @default.
• W2075417967 creator A5076706439 @default.
• W2075417967 creator A5077082770 @default.
• W2075417967 creator A5086764033 @default.
• W2075417967 creator A5090814913 @default.
• W2075417967 creator A5091503377 @default.
• W2075417967 date "2011-02-01" @default.
• W2075417967 modified "2023-10-12" @default.
• W2075417967 title "Risk Factors for Recurrent Syncope and Subsequent Fatal or Near-Fatal Events in Children and Adolescents With Long QT Syndrome" @default.
• W2075417967 cites W1968095129 @default.
• W2075417967 cites W1996802734 @default.
• W2075417967 cites W2000620739 @default.
• W2075417967 cites W2003236441 @default.
• W2075417967 cites W2004894384 @default.
• W2075417967 cites W2019045599 @default.
• W2075417967 cites W2029433670 @default.
• W2075417967 cites W2053559419 @default.
• W2075417967 cites W2077818517 @default.
• W2075417967 cites W2079038230 @default.
• W2075417967 cites W2091453055 @default.
• W2075417967 cites W2092648747 @default.
• W2075417967 cites W2126428415 @default.
• W2075417967 cites W2133151374 @default.
• W2075417967 cites W2133663070 @default.
• W2075417967 cites W2134150702 @default.
• W2075417967 cites W2145159920 @default.
• W2075417967 cites W2156937709 @default.
• W2075417967 cites W2159701763 @default.
• W2075417967 doi "https://doi.org/10.1016/j.jacc.2010.10.025" @default.
• W2075417967 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3052409" @default.
• W2075417967 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21329841" @default.
• W2075417967 hasPublicationYear "2011" @default.
• W2075417967 type Work @default.
• W2075417967 sameAs 2075417967 @default.
• W2075417967 citedByCount "99" @default.
• W2075417967 countsByYear W20754179672012 @default.
• W2075417967 countsByYear W20754179672013 @default.
• W2075417967 countsByYear W20754179672014 @default.
• W2075417967 countsByYear W20754179672015 @default.
• W2075417967 countsByYear W20754179672016 @default.
• W2075417967 countsByYear W20754179672017 @default.
• W2075417967 countsByYear W20754179672018 @default.
• W2075417967 countsByYear W20754179672019 @default.
• W2075417967 countsByYear W20754179672020 @default.
• W2075417967 countsByYear W20754179672021 @default.
• W2075417967 countsByYear W20754179672022 @default.
• W2075417967 countsByYear W20754179672023 @default.
• W2075417967 crossrefType "journal-article" @default.
• W2075417967 hasAuthorship W2075417967A5001410007 @default.
• W2075417967 hasAuthorship W2075417967A5002121570 @default.
• W2075417967 hasAuthorship W2075417967A5008966758 @default.
• W2075417967 hasAuthorship W2075417967A5010388094 @default.
• W2075417967 hasAuthorship W2075417967A5012507741 @default.
• W2075417967 hasAuthorship W2075417967A5021196395 @default.
• W2075417967 hasAuthorship W2075417967A5025486359 @default.
• W2075417967 hasAuthorship W2075417967A5038126690 @default.
• W2075417967 hasAuthorship W2075417967A5049150501 @default.
• W2075417967 hasAuthorship W2075417967A5055125250 @default.
• W2075417967 hasAuthorship W2075417967A5057507865 @default.
• W2075417967 hasAuthorship W2075417967A5059052503 @default.
• W2075417967 hasAuthorship W2075417967A5066716873 @default.
• W2075417967 hasAuthorship W2075417967A5075060212 @default.
• W2075417967 hasAuthorship W2075417967A5076422519 @default.
• W2075417967 hasAuthorship W2075417967A5076706439 @default.
• W2075417967 hasAuthorship W2075417967A5077082770 @default.
• W2075417967 hasAuthorship W2075417967A5086764033 @default.
• W2075417967 hasAuthorship W2075417967A5090814913 @default.
• W2075417967 hasAuthorship W2075417967A5091503377 @default.
• W2075417967 hasBestOaLocation W20754179671 @default.
• W2075417967 hasConcept C118441451 @default.
• W2075417967 hasConcept C126322002 @default.
• W2075417967 hasConcept C164705383 @default.
• W2075417967 hasConcept C187212893 @default.
• W2075417967 hasConcept C207103383 @default.
• W2075417967 hasConcept C2779703243 @default.
• W2075417967 hasConcept C2780703726 @default.
• W2075417967 hasConcept C44249647 @default.
• W2075417967 hasConcept C71924100 @default.
• W2075417967 hasConceptScore W2075417967C118441451 @default.
• W2075417967 hasConceptScore W2075417967C126322002 @default.
• W2075417967 hasConceptScore W2075417967C164705383 @default.
• W2075417967 hasConceptScore W2075417967C187212893 @default.

• next