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• W2075443006 abstract "The crawling locomotion and shape of eukaryotic cells have been associated with the stochastic molecular dynamics of actin and its protein regulators, chiefly Arp2/3 and Rho family GTPases, in making a cytoskeleton meshwork within cell extensions. However, the cell's actin-dependent oscillatory shape and extension dynamics may also yield insights into locomotory mechanisms. Confocal observations of live Dictyostelium cells, expressing a green fluorescent protein-actin fusion protein, demonstrate oscillating supramolecular patterns of filamentous actin throughout the cell, which generate pseudopodia at the cell edge. The distinctively dissipative spatio-temporal behavior of these structures provides strong evidence that reversible actin filament assembly propagates as a self-organized, chemical reaction-diffusion wave." @default.
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• W2075443006 date "2001-11-29" @default.
• W2075443006 modified "2023-10-18" @default.
• W2075443006 title "F-actin assembly in<i>Dictyostelium</i>cell locomotion and shape oscillations propagates as a self-organized reaction-diffusion wave" @default.
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• W2075443006 doi "https://doi.org/10.1016/s0014-5793(01)03207-0" @default.
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