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- W2075456878 abstract "A potentially lethal chlorpropamide overdose in a patient with chronic renal failure on long-term hemodialysis was treated by two courses of charcoal hemoperfusion. Hemoperfusion shortened the half-life clearance of the drug from a mean value of 93.6 to 3.4 hours. Calculation of the fractional extraction indicated that hemoperfusion reduced the body burden of the drug by 24% and 19% (mean values) during the first and second hours of treatment, respectively. We conclude that charcoal hemoperfusion should be considered a definitive therapeutic option in such cases." @default.
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- W2075456878 date "1987-12-01" @default.
- W2075456878 modified "2023-09-25" @default.
- W2075456878 title "Chlorpropamide Overdose in Renal Failure: Management with Charcoal Hemoperfusion" @default.
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- W2075456878 doi "https://doi.org/10.1016/s0272-6386(87)80193-2" @default.
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