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- W2075572308 abstract "Abstract The periodic administration of any of a number of convulsive agents has been reported to produce a progressive increase in the severity of the elicited motor seizures (kindling), whereas an elevation in the seizure threshold is the widely reported consequence of a series of electroconvulsive shocks. However, in the present experiments electroconvulsive shocks administered once every 3 days to rats at either of two suprathreshold intensities produced a progressive increase in the severity of the motor seizure pattern. At short intervals (1 hr) the usual decline in motor seizure severity was observed whereas there were no systematic changes at an intermediate interval (1 day). Thus, periodic electroconvulsive shocks produce progressive effects comparable to those produced by the periodic application of other convulsive agents." @default.
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- W2075572308 date "1976-05-01" @default.
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- W2075572308 title "Progressive intensification of motor seizures produced by periodic electroconvulsive shock" @default.
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- W2075572308 doi "https://doi.org/10.1016/0014-4886(76)90266-1" @default.
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