FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2075645163> ?p ?o ?g. }

• W2075645163 endingPage "2048" @default.
• W2075645163 startingPage "2035" @default.
• W2075645163 abstract "Antibody-mediated rejection (AMR) is a unique, significant, and often severe form of allograft rejection that is not amenable to treatment with standard immunosuppressive medications. Significant advances have occurred in our ability to predict patients at risk for, and to diagnose, AMR. These advances include the development of newer anti-human leukocyte antigen (HLA)-antibody detection techniques and assays for non-HLA antibodies associated with AMR. The pathophysiology of AMR suggests a prime role for antibodies, B cells and plasma cells, but other effector molecules, especially the complement system, point to potential targets that could modify the AMR process. An emerging and potentially larger problem is the development of chronic AMR (CAMR) resulting from de novo donor-specific anti-HLA antibodies (DSA) that emerge more than 100 days posttransplantation. Therapeutic options include: (1) High-dose intravenously administered immunoglobulin (IVIG), which has many potential benefits. (2) The use of IVIG + rituximab (anti-CD20, anti-B cell). (3) The combination of plasmapheresis (PP) + low-dose IVIG with or without rituximab. Data support the efficacy of all of the above approaches. Newer approaches to treating AMR include using the proteosome inhibitor (bortezomib), which induces apoptosis in plasma cells, and eculizumab (anti-C5, anticomplement monoclonal antibody)." @default.
• W2075645163 created "2016-06-24" @default.
• W2075645163 creator A5002039083 @default.
• W2075645163 creator A5021943951 @default.
• W2075645163 creator A5036281463 @default.
• W2075645163 creator A5044616722 @default.
• W2075645163 creator A5047499121 @default.
• W2075645163 creator A5067740422 @default.
• W2075645163 creator A5071314630 @default.
• W2075645163 creator A5072310025 @default.
• W2075645163 creator A5076738806 @default.
• W2075645163 date "2010-01-14" @default.
• W2075645163 modified "2023-10-16" @default.
• W2075645163 title "Advances in diagnosing and managing antibody-mediated rejection" @default.
• W2075645163 cites W1496009765 @default.
• W2075645163 cites W1505562530 @default.
• W2075645163 cites W1573509127 @default.
• W2075645163 cites W1964180982 @default.
• W2075645163 cites W1966348678 @default.
• W2075645163 cites W1966455480 @default.
• W2075645163 cites W1968889356 @default.
• W2075645163 cites W1971744909 @default.
• W2075645163 cites W1975300245 @default.
• W2075645163 cites W1982528317 @default.
• W2075645163 cites W1983537514 @default.
• W2075645163 cites W1985240611 @default.
• W2075645163 cites W1986678613 @default.
• W2075645163 cites W1987068568 @default.
• W2075645163 cites W1989449493 @default.
• W2075645163 cites W1989569525 @default.
• W2075645163 cites W1992883814 @default.
• W2075645163 cites W1994412969 @default.
• W2075645163 cites W1995498454 @default.
• W2075645163 cites W1997337646 @default.
• W2075645163 cites W1998522073 @default.
• W2075645163 cites W2001321215 @default.
• W2075645163 cites W2002448034 @default.
• W2075645163 cites W2006521244 @default.
• W2075645163 cites W2007166703 @default.
• W2075645163 cites W2008578152 @default.
• W2075645163 cites W2009888511 @default.
• W2075645163 cites W2013206265 @default.
• W2075645163 cites W2019690943 @default.
• W2075645163 cites W2021227791 @default.
• W2075645163 cites W2028897583 @default.
• W2075645163 cites W2031276271 @default.
• W2075645163 cites W2031809342 @default.
• W2075645163 cites W2034340957 @default.
• W2075645163 cites W2035433348 @default.
• W2075645163 cites W2038789463 @default.
• W2075645163 cites W2041288261 @default.
• W2075645163 cites W2041352623 @default.
• W2075645163 cites W2047694801 @default.
• W2075645163 cites W2051266349 @default.
• W2075645163 cites W2051666192 @default.
• W2075645163 cites W2058272020 @default.
• W2075645163 cites W2058424528 @default.
• W2075645163 cites W2059446551 @default.
• W2075645163 cites W2061888899 @default.
• W2075645163 cites W2066846899 @default.
• W2075645163 cites W2067811565 @default.
• W2075645163 cites W2068957613 @default.
• W2075645163 cites W2070239044 @default.
• W2075645163 cites W2070255464 @default.
• W2075645163 cites W2072205634 @default.
• W2075645163 cites W2076843879 @default.
• W2075645163 cites W2077570217 @default.
• W2075645163 cites W2079246366 @default.
• W2075645163 cites W2087929136 @default.
• W2075645163 cites W2092628378 @default.
• W2075645163 cites W2094487124 @default.
• W2075645163 cites W2098773501 @default.
• W2075645163 cites W2099801548 @default.
• W2075645163 cites W2112331465 @default.
• W2075645163 cites W2114947032 @default.
• W2075645163 cites W2118994799 @default.
• W2075645163 cites W2121010294 @default.
• W2075645163 cites W2121183119 @default.
• W2075645163 cites W2125843015 @default.
• W2075645163 cites W2126678530 @default.
• W2075645163 cites W2130820062 @default.
• W2075645163 cites W2136732030 @default.
• W2075645163 cites W2139856839 @default.
• W2075645163 cites W2166277046 @default.
• W2075645163 cites W2168870572 @default.
• W2075645163 cites W2170256066 @default.
• W2075645163 cites W2170363310 @default.
• W2075645163 cites W2323651049 @default.
• W2075645163 cites W2323727101 @default.
• W2075645163 cites W4241819966 @default.
• W2075645163 cites W60759546 @default.
• W2075645163 doi "https://doi.org/10.1007/s00467-009-1386-4" @default.
• W2075645163 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2923704" @default.
• W2075645163 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20077121" @default.
• W2075645163 hasPublicationYear "2010" @default.
• W2075645163 type Work @default.
• W2075645163 sameAs 2075645163 @default.
• W2075645163 citedByCount "68" @default.

• next