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- W2075653178 abstract "Abstract The influence of the protein synthesis inhibitor chloramphenicol (CHL) on the chromosome-breaking action of 8-ethoxycaffeine (EOC) and 6-methylcoumarin (6-MC) has been investigated in Vicia faba root meristems. CHL, when applied as a post-treatment, increased the frequency of true chromatid breaks, achromatic lesions (gaps) and subchromatid exchanges induced by EOC. When given with the mutagen, CHL failed to show any significant effect. A greater yield of subchromatid exchanges was obtained after a 6-MC treatment followed by CHL than after 6-MC alone; but less significant differences in chromatid break frequencies were observed. The possible implications of these findings for the problem of the mechanism of action of mutagens effective in the DNA-postsynthetic phase (G 2 ) are discussed." @default.
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- W2075653178 date "1967-09-01" @default.
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- W2075653178 title "The effect of chloramphenicol on the chromosome-breaking action of 8-ethoxycaffeine and 6-methylcoumarin in Vicia faba" @default.
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- W2075653178 doi "https://doi.org/10.1016/0027-5107(67)90047-4" @default.
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