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• W2075657917 endingPage "214" @default.
• W2075657917 startingPage "204" @default.
• W2075657917 abstract "Abstract Circadian rhythmicity is a fundamental characteristic of organisms, which helps ensure that vital functions occur in an appropriate and precise temporal sequence and in accordance with cyclic environmental changes. Living beings are endowed with a system of biological clocks that measure time on a 24‐hr basis, termed the circadian timing system. In mammals, the system is organized as a master clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus, commanding peripheral clocks located in almost every tissue of the body. At the cell level, interlocking transcription/translation feedback loops of the genes Bmal‐1, Clock, Per1–2, and Cry1–2, named clock genes, and their protein products results in circadian oscillation of clock genes and of genes involved in almost every cellular function. During gestation, the conceptus follows a complex and dynamic program by which it is simultaneously fit to develop and live in a circadian environment provided by its mother and to prepare for the very different environment that it will experience after birth. It has been known for a number of years that the mother tells the fetus the time of day and season of the year, and that the fetus uses this information to set the phase of fetal and neonatal circadian rhythms. There is evidence that the maternal rhythm of melatonin is one of the time signals to the fetus. In the last few years, the study of the development of the circadian system has turned to the investigation of the oscillatory expression of clock genes and their possible role in development, and to answering questions on the organization of the fetal circadian system. Emerging evidence shows that clock genes are expressed in the oocyte and during early and late development in embryo/fetal organs in the rat and in a fetal primate. The data available raise the intriguing possibility that the fetal SCN and fetal tissues may be peripheral clocks commanded by separate maternal signals. The rapid methodological and conceptual advances on chronobiology may help to unravel how the developing embryo and fetus faces time in this plastic period of life. Birth Defects Research (Part C) 81:204–214, 2007. © 2007 Wiley‐Liss, Inc." @default.
• W2075657917 created "2016-06-24" @default.
• W2075657917 creator A5019662778 @default.
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• W2075657917 date "2007-09-01" @default.
• W2075657917 modified "2023-10-16" @default.
• W2075657917 title "Circadian clocks during embryonic and fetal development" @default.
• W2075657917 cites W1013059913 @default.
• W2075657917 cites W1481897226 @default.
• W2075657917 cites W1511863177 @default.
• W2075657917 cites W1557411044 @default.
• W2075657917 cites W1594088585 @default.
• W2075657917 cites W1968602579 @default.
• W2075657917 cites W1970442836 @default.
• W2075657917 cites W1970546996 @default.
• W2075657917 cites W1972142783 @default.
• W2075657917 cites W1972753027 @default.
• W2075657917 cites W1974129885 @default.
• W2075657917 cites W1975128253 @default.
• W2075657917 cites W1976909767 @default.
• W2075657917 cites W1979606491 @default.
• W2075657917 cites W1982104209 @default.
• W2075657917 cites W1984639295 @default.
• W2075657917 cites W1987662918 @default.
• W2075657917 cites W1989011389 @default.
• W2075657917 cites W1989837009 @default.
• W2075657917 cites W1990192893 @default.
• W2075657917 cites W1991298209 @default.
• W2075657917 cites W1991853693 @default.
• W2075657917 cites W1993901564 @default.
• W2075657917 cites W1998606595 @default.
• W2075657917 cites W2002418365 @default.
• W2075657917 cites W2003302378 @default.
• W2075657917 cites W2009999546 @default.
• W2075657917 cites W2010104326 @default.
• W2075657917 cites W2010487243 @default.
• W2075657917 cites W2011334413 @default.
• W2075657917 cites W2011827067 @default.
• W2075657917 cites W2012509672 @default.
• W2075657917 cites W2014313900 @default.
• W2075657917 cites W2015478623 @default.
• W2075657917 cites W2016407413 @default.
• W2075657917 cites W2019394392 @default.
• W2075657917 cites W2020960148 @default.
• W2075657917 cites W2021654192 @default.
• W2075657917 cites W2024450505 @default.
• W2075657917 cites W2032185030 @default.
• W2075657917 cites W2036024950 @default.
• W2075657917 cites W2036177439 @default.
• W2075657917 cites W2037104566 @default.
• W2075657917 cites W2040629892 @default.
• W2075657917 cites W2047902467 @default.
• W2075657917 cites W2053438062 @default.
• W2075657917 cites W2055971382 @default.
• W2075657917 cites W2060925737 @default.
• W2075657917 cites W2068648361 @default.
• W2075657917 cites W2076794882 @default.
• W2075657917 cites W2077932483 @default.
• W2075657917 cites W2080735372 @default.
• W2075657917 cites W2091393924 @default.
• W2075657917 cites W2093344683 @default.
• W2075657917 cites W2093526792 @default.
• W2075657917 cites W2096186352 @default.
• W2075657917 cites W2100382353 @default.
• W2075657917 cites W2100416578 @default.
• W2075657917 cites W2101600063 @default.
• W2075657917 cites W2104290916 @default.
• W2075657917 cites W2104901413 @default.
• W2075657917 cites W2108783682 @default.
• W2075657917 cites W2109469421 @default.
• W2075657917 cites W2109851694 @default.
• W2075657917 cites W2113511986 @default.
• W2075657917 cites W2115505876 @default.
• W2075657917 cites W2123064936 @default.
• W2075657917 cites W2124659072 @default.
• W2075657917 cites W2126529900 @default.
• W2075657917 cites W2128825258 @default.
• W2075657917 cites W2129265609 @default.
• W2075657917 cites W2130153219 @default.
• W2075657917 cites W2130498291 @default.
• W2075657917 cites W2130859436 @default.
• W2075657917 cites W2131192824 @default.
• W2075657917 cites W2132358997 @default.
• W2075657917 cites W2132443457 @default.
• W2075657917 cites W2132681815 @default.
• W2075657917 cites W2134377844 @default.
• W2075657917 cites W2135221436 @default.
• W2075657917 cites W2140987470 @default.
• W2075657917 cites W2144045637 @default.
• W2075657917 cites W2145237902 @default.
• W2075657917 cites W2147712103 @default.
• W2075657917 cites W2148838323 @default.
• W2075657917 cites W2153042537 @default.
• W2075657917 cites W2154391625 @default.
• W2075657917 cites W2160091872 @default.
• W2075657917 cites W2162878054 @default.
• W2075657917 cites W2163298351 @default.

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