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- W2075670174 abstract "<h2>Abstract</h2> The effect of PGE<sub>1</sub> and PGA<sub>1</sub> intravenous infusion (2/μg/min) on plasma glucose and glucagon levels was investigated in normal, sympathectomized and propranolol-treated rats. PGE<sub>1</sub> infusion significantly increased glucose and glucagon levels, while PGA<sub>1</sub> had no effect. Since the dose of PGE<sub>1</sub> used in this study was able to reduce the arterial blood pressure by about 20%, the possibility that PGE<sub>1</sub> acted indirectly through a reflex sympathetic overactivity was tested. The increases in plasma glucagon induced by PGE<sub>1</sub> occurred also in sympathectomized or in beta-blocked animals. Thus, it was possible to exclude a sympathetic mediation or a direct stimulation of pancreatic beta-receptors as a likely mechanism of PGE<sub>1</sub> action." @default.
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- W2075670174 title "Influence of prostaglandins on plasma glucagon levels in the rat" @default.
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- W2075670174 doi "https://doi.org/10.1016/0026-0495(76)90041-x" @default.
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