FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2075740040> ?p ?o ?g. }

• W2075740040 endingPage "188" @default.
• W2075740040 startingPage "181" @default.
• W2075740040 abstract "Twist, a basic helix-loop-helix transcription factor, promotes cancer cell epithelial-mesenchymal transition and metastasis. Here, we aimed to examine the association between Twist expression and lymphovascular space involvement for early-stage cervical carcinoma. Paraffin sections from 90 patients with stage Ib to IIb cervical carcinoma were immunostained with Twist antibody, and the staining intensities were semiquantitatively evaluated. Of the 90 cervical carcinoma specimens examined in this study, 51 (56.7%) were negative for Twist and 39 (43.3%) were positive for Twist immunoreactivity. The 5-year overall survival rates of patients in the Twist-negative and Twist-positive groups were 98.0% and 75.8%, respectively. Univariate and multivariate analyses demonstrated that Twist expression was an independent prognostic factor for overall survival and recurrence-free survival (univariate: P = .0069 [overall survival], P = .0092 [recurrence-free survival]: multivariate: P = .0118 [overall survival], P = .0118 [recurrence-free survival]). On stratifying based on the negative lymphovascular space involvement status, the overall survival and recurrence-free survival of patients in the Twist-negative group was the same as that of those in the Twist-positive group (log-rank: P = .262 [recurrence-free survival], P = .899 [overall survival]). In contrast, with lymphovascular space involvement, a significantly poorer recurrence-free survival was predicted for patients in the Twist-positive group compared with that in the Twist-negative group (P = .0021). Twelve (75.0%) of 16 patients showing recurrence belonged to the Twist-positive group, and 83.3% (10/12) of them experienced recurrence in distant organs or the peritoneal cavity. This study suggested that the assessment of the Twist immunoreactivity and lymphovascular space involvement may distinguish high- from low-risk patients with locally invasive cervical carcinoma." @default.
• W2075740040 created "2016-06-24" @default.
• W2075740040 creator A5021170427 @default.
• W2075740040 creator A5021636084 @default.
• W2075740040 creator A5049246136 @default.
• W2075740040 creator A5058903905 @default.
• W2075740040 creator A5076332969 @default.
• W2075740040 creator A5078859785 @default.
• W2075740040 creator A5081702111 @default.
• W2075740040 creator A5086011356 @default.
• W2075740040 date "2013-02-01" @default.
• W2075740040 modified "2023-09-27" @default.
• W2075740040 title "Expression of Twist enhances risk of poor oncologic outcome in patients with stage Ib to II cervical carcinoma with lymphovascular space involvement" @default.
• W2075740040 cites W1866991157 @default.
• W2075740040 cites W1964459129 @default.
• W2075740040 cites W1971759252 @default.
• W2075740040 cites W1981126547 @default.
• W2075740040 cites W1983593066 @default.
• W2075740040 cites W1987318948 @default.
• W2075740040 cites W2000307839 @default.
• W2075740040 cites W2014309688 @default.
• W2075740040 cites W2014632820 @default.
• W2075740040 cites W2026213731 @default.
• W2075740040 cites W2031670925 @default.
• W2075740040 cites W2036008499 @default.
• W2075740040 cites W2043797012 @default.
• W2075740040 cites W2044412743 @default.
• W2075740040 cites W2047172303 @default.
• W2075740040 cites W2051940224 @default.
• W2075740040 cites W2053448532 @default.
• W2075740040 cites W2055353313 @default.
• W2075740040 cites W2058437379 @default.
• W2075740040 cites W2106787323 @default.
• W2075740040 cites W2128318768 @default.
• W2075740040 cites W2139409822 @default.
• W2075740040 cites W2148284233 @default.
• W2075740040 cites W2164741887 @default.
• W2075740040 cites W2171896038 @default.
• W2075740040 doi "https://doi.org/10.1016/j.humpath.2012.05.015" @default.
• W2075740040 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22974479" @default.
• W2075740040 hasPublicationYear "2013" @default.
• W2075740040 type Work @default.
• W2075740040 sameAs 2075740040 @default.
• W2075740040 citedByCount "9" @default.
• W2075740040 countsByYear W20757400402014 @default.
• W2075740040 countsByYear W20757400402015 @default.
• W2075740040 countsByYear W20757400402016 @default.
• W2075740040 countsByYear W20757400402017 @default.
• W2075740040 countsByYear W20757400402020 @default.
• W2075740040 crossrefType "journal-article" @default.
• W2075740040 hasAuthorship W2075740040A5021170427 @default.
• W2075740040 hasAuthorship W2075740040A5021636084 @default.
• W2075740040 hasAuthorship W2075740040A5049246136 @default.
• W2075740040 hasAuthorship W2075740040A5058903905 @default.
• W2075740040 hasAuthorship W2075740040A5076332969 @default.
• W2075740040 hasAuthorship W2075740040A5078859785 @default.
• W2075740040 hasAuthorship W2075740040A5081702111 @default.
• W2075740040 hasAuthorship W2075740040A5086011356 @default.
• W2075740040 hasConcept C10515644 @default.
• W2075740040 hasConcept C121608353 @default.
• W2075740040 hasConcept C126322002 @default.
• W2075740040 hasConcept C143998085 @default.
• W2075740040 hasConcept C144301174 @default.
• W2075740040 hasConcept C146357865 @default.
• W2075740040 hasConcept C151730666 @default.
• W2075740040 hasConcept C2524010 @default.
• W2075740040 hasConcept C2776196297 @default.
• W2075740040 hasConcept C2776283816 @default.
• W2075740040 hasConcept C2777546739 @default.
• W2075740040 hasConcept C2778740770 @default.
• W2075740040 hasConcept C2778893926 @default.
• W2075740040 hasConcept C2779013556 @default.
• W2075740040 hasConcept C33923547 @default.
• W2075740040 hasConcept C38180746 @default.
• W2075740040 hasConcept C71924100 @default.
• W2075740040 hasConcept C76419328 @default.
• W2075740040 hasConcept C86803240 @default.
• W2075740040 hasConcept C90924648 @default.
• W2075740040 hasConceptScore W2075740040C10515644 @default.
• W2075740040 hasConceptScore W2075740040C121608353 @default.
• W2075740040 hasConceptScore W2075740040C126322002 @default.
• W2075740040 hasConceptScore W2075740040C143998085 @default.
• W2075740040 hasConceptScore W2075740040C144301174 @default.
• W2075740040 hasConceptScore W2075740040C146357865 @default.
• W2075740040 hasConceptScore W2075740040C151730666 @default.
• W2075740040 hasConceptScore W2075740040C2524010 @default.
• W2075740040 hasConceptScore W2075740040C2776196297 @default.
• W2075740040 hasConceptScore W2075740040C2776283816 @default.
• W2075740040 hasConceptScore W2075740040C2777546739 @default.
• W2075740040 hasConceptScore W2075740040C2778740770 @default.
• W2075740040 hasConceptScore W2075740040C2778893926 @default.
• W2075740040 hasConceptScore W2075740040C2779013556 @default.
• W2075740040 hasConceptScore W2075740040C33923547 @default.
• W2075740040 hasConceptScore W2075740040C38180746 @default.
• W2075740040 hasConceptScore W2075740040C71924100 @default.
• W2075740040 hasConceptScore W2075740040C76419328 @default.
• W2075740040 hasConceptScore W2075740040C86803240 @default.
• W2075740040 hasConceptScore W2075740040C90924648 @default.

• next