FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2075853669> ?p ?o ?g. }

• W2075853669 endingPage "467" @default.
• W2075853669 startingPage "459" @default.
• W2075853669 abstract "Highly integrated anatomic and functional interactions between the cerebrum and the cerebellum during development have been reported. In our previous study, we conducted a proteome analysis to identify the proteins present in the congenital noncommunicating hydrocephalus in the cerebellum. We found higher expression of high-mobility group box-1 protein (HMGB-1) in hydrocephalic H-Tx rats.We studied the expression pattern of HMGB-1 in the cerebellum.We studied congenital hydrocephalic H-Tx rats aged 1 day and 7 days along with age-matched nonhydrocephalic H-Tx and Sprague-Dawley rats as controls. Gene and protein expressions of HMGB-1 in the cerebellum were assayed by real-time polymerase chain reaction and Western blotting, respectively; furthermore, immunohistochemical analyses were performed by using HMGB-1 (indicator of apoptosis), single-stranded DNA; adhesion factor related to cell migration, HNK-1; and the Purkinje cell-specific antibody, calbindin.Cytoplasmic HMGB-1 expression observed in Purkinje cells in the 1-day-old hydrocephalic group was stronger than that in the nonhydrocephalic and Sprague-Dawley groups. Double fluorescent staining with single-stranded DNA confirmed that Purkinje cells were undergoing apoptosis. HNK-1 expression was lower in the Purkinje cell layer in the 7-day-old rats in the hydrocephalic group, and Purkinje cells were disrupted in comparison with the control groups. Morphological changes in the cerebellum were observed in the 7-day-old rats in the hydrocephalic group in comparison with the control groups.Our results suggest that cerebellar neuronal cell damage in the early postnatal period may be related to the higher expression of HMGB-1 in the Purkinje cells." @default.
• W2075853669 created "2016-06-24" @default.
• W2075853669 creator A5038710628 @default.
• W2075853669 creator A5040424370 @default.
• W2075853669 creator A5040570107 @default.
• W2075853669 creator A5044194892 @default.
• W2075853669 creator A5054184031 @default.
• W2075853669 date "2013-03-01" @default.
• W2075853669 modified "2023-09-25" @default.
• W2075853669 title "Cerebellar Purkinje Cells Exhibit Increased Expression of HMGB-1 and Apoptosis in Congenital Hydrocephalic H-Tx Rats" @default.
• W2075853669 cites W1978457585 @default.
• W2075853669 cites W1980301760 @default.
• W2075853669 cites W1991338618 @default.
• W2075853669 cites W1992889156 @default.
• W2075853669 cites W1998188336 @default.
• W2075853669 cites W2014260588 @default.
• W2075853669 cites W2019084238 @default.
• W2075853669 cites W2048813357 @default.
• W2075853669 cites W2060068387 @default.
• W2075853669 cites W2064452340 @default.
• W2075853669 cites W2068318330 @default.
• W2075853669 cites W2075176810 @default.
• W2075853669 cites W2076235538 @default.
• W2075853669 cites W2079003822 @default.
• W2075853669 cites W2079777059 @default.
• W2075853669 cites W2080246930 @default.
• W2075853669 cites W2082765963 @default.
• W2075853669 cites W2084468489 @default.
• W2075853669 cites W2090896550 @default.
• W2075853669 cites W2091536726 @default.
• W2075853669 cites W2092717199 @default.
• W2075853669 cites W2108888571 @default.
• W2075853669 cites W2111041043 @default.
• W2075853669 cites W2116023559 @default.
• W2075853669 cites W2124002755 @default.
• W2075853669 cites W2137788719 @default.
• W2075853669 cites W2140065103 @default.
• W2075853669 cites W2140190130 @default.
• W2075853669 cites W2247270108 @default.
• W2075853669 cites W57162773 @default.
• W2075853669 doi "https://doi.org/10.1227/neu.0b013e31827fcd83" @default.
• W2075853669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23208066" @default.
• W2075853669 hasPublicationYear "2013" @default.
• W2075853669 type Work @default.
• W2075853669 sameAs 2075853669 @default.
• W2075853669 citedByCount "4" @default.
• W2075853669 countsByYear W20758536692015 @default.
• W2075853669 countsByYear W20758536692016 @default.
• W2075853669 countsByYear W20758536692020 @default.
• W2075853669 countsByYear W20758536692023 @default.
• W2075853669 crossrefType "journal-article" @default.
• W2075853669 hasAuthorship W2075853669A5038710628 @default.
• W2075853669 hasAuthorship W2075853669A5040424370 @default.
• W2075853669 hasAuthorship W2075853669A5040570107 @default.
• W2075853669 hasAuthorship W2075853669A5044194892 @default.
• W2075853669 hasAuthorship W2075853669A5054184031 @default.
• W2075853669 hasConcept C126322002 @default.
• W2075853669 hasConcept C134018914 @default.
• W2075853669 hasConcept C142724271 @default.
• W2075853669 hasConcept C190283241 @default.
• W2075853669 hasConcept C204232928 @default.
• W2075853669 hasConcept C26265296 @default.
• W2075853669 hasConcept C2778472085 @default.
• W2075853669 hasConcept C2779652256 @default.
• W2075853669 hasConcept C2780680797 @default.
• W2075853669 hasConcept C55493867 @default.
• W2075853669 hasConcept C71924100 @default.
• W2075853669 hasConcept C86803240 @default.
• W2075853669 hasConceptScore W2075853669C126322002 @default.
• W2075853669 hasConceptScore W2075853669C134018914 @default.
• W2075853669 hasConceptScore W2075853669C142724271 @default.
• W2075853669 hasConceptScore W2075853669C190283241 @default.
• W2075853669 hasConceptScore W2075853669C204232928 @default.
• W2075853669 hasConceptScore W2075853669C26265296 @default.
• W2075853669 hasConceptScore W2075853669C2778472085 @default.
• W2075853669 hasConceptScore W2075853669C2779652256 @default.
• W2075853669 hasConceptScore W2075853669C2780680797 @default.
• W2075853669 hasConceptScore W2075853669C55493867 @default.
• W2075853669 hasConceptScore W2075853669C71924100 @default.
• W2075853669 hasConceptScore W2075853669C86803240 @default.
• W2075853669 hasIssue "3" @default.
• W2075853669 hasLocation W20758536691 @default.
• W2075853669 hasLocation W20758536692 @default.
• W2075853669 hasOpenAccess W2075853669 @default.
• W2075853669 hasPrimaryLocation W20758536691 @default.
• W2075853669 hasRelatedWork W1964050585 @default.
• W2075853669 hasRelatedWork W1967887008 @default.
• W2075853669 hasRelatedWork W1976180052 @default.
• W2075853669 hasRelatedWork W2020280724 @default.
• W2075853669 hasRelatedWork W2052690275 @default.
• W2075853669 hasRelatedWork W2089328257 @default.
• W2075853669 hasRelatedWork W2137283177 @default.
• W2075853669 hasRelatedWork W2300186862 @default.
• W2075853669 hasRelatedWork W2936968113 @default.
• W2075853669 hasRelatedWork W1964891810 @default.
• W2075853669 hasVolume "72" @default.
• W2075853669 isParatext "false" @default.
• W2075853669 isRetracted "false" @default.

• next