FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2075955797> ?p ?o ?g. }

• W2075955797 endingPage "378" @default.
• W2075955797 startingPage "372" @default.
• W2075955797 abstract "Up to now, the mechanisms responsible for progression from noninvasive to invasive breast cancer have remained obscure. Tenascin is an extracellular matrix glycoprotein, present in embryonal and fetal tissues, which is also found in the stroma of various benign and malignant pathologies. We studied the expression and immunohistochemical behavior of tenascin in specimens of invasive and preinvasive breast cancer in order to assess its potential role as a marker for tumor invasion.Sixty-eight specimens including 29 noninvasive ductal cancers, 12 invasive ductal cancers, 5 adenoses, 7 fibroadenomas, and 15 samples of normal human breast tissue were evaluated. An immunofluorescent microscopic technique was used for analysis of the localization and distribution of tenascin. Paraffin-embedded biopsies were incubated with primary monoclonal anti-tenascin antibodies (1:25, Dako-tenascin, TN2). Subsequently, trimethylrhodamine-isothiocyanate-conjugated secondary antibodies (rabbit anti-mouse immunglobulins (Dakopatts, Denmark) were added to visualize the protein.A significant tenascin expression was observed around the ducts in all samples of patients with preinvasive breast cancers. Intensive staining was also found in the periductal stroma of all specimens of patients with invasive breast cancers. Benign breast lesions showed weaker reactivity. No tenascin expression was detectable in normal human breasts, while tissue samples of in situ cancers presented variable staining intensities positively correlating with the degree of differentiation.Tenascin immunofluorescence may prove a suitable and helpful adjunct for diagnosing malignant disease and for predicting the invasive potential of premalignant breast lesions." @default.
• W2075955797 created "2016-06-24" @default.
• W2075955797 creator A5012917847 @default.
• W2075955797 creator A5027488429 @default.
• W2075955797 creator A5034369406 @default.
• W2075955797 creator A5066670744 @default.
• W2075955797 date "2000-12-01" @default.
• W2075955797 modified "2023-10-10" @default.
• W2075955797 title "Tenascin—A Marker for the Malignant Potential of Preinvasive Breast Cancers" @default.
• W2075955797 cites W1852165254 @default.
• W2075955797 cites W1970855600 @default.
• W2075955797 cites W1974785026 @default.
• W2075955797 cites W1976430153 @default.
• W2075955797 cites W1985723648 @default.
• W2075955797 cites W1986904372 @default.
• W2075955797 cites W1988297300 @default.
• W2075955797 cites W2010500685 @default.
• W2075955797 cites W2011008267 @default.
• W2075955797 cites W2014867114 @default.
• W2075955797 cites W2024058845 @default.
• W2075955797 cites W2031240430 @default.
• W2075955797 cites W2032098468 @default.
• W2075955797 cites W2039374288 @default.
• W2075955797 cites W2041163630 @default.
• W2075955797 cites W2048140020 @default.
• W2075955797 cites W2051313312 @default.
• W2075955797 cites W2055006843 @default.
• W2075955797 cites W2056848519 @default.
• W2075955797 cites W2059375645 @default.
• W2075955797 cites W2088500333 @default.
• W2075955797 cites W2098840127 @default.
• W2075955797 cites W2101843767 @default.
• W2075955797 cites W2142376043 @default.
• W2075955797 cites W2143315617 @default.
• W2075955797 cites W2144775586 @default.
• W2075955797 cites W2168432310 @default.
• W2075955797 cites W2169680251 @default.
• W2075955797 doi "https://doi.org/10.1006/gyno.2000.5978" @default.
• W2075955797 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11104607" @default.
• W2075955797 hasPublicationYear "2000" @default.
• W2075955797 type Work @default.
• W2075955797 sameAs 2075955797 @default.
• W2075955797 citedByCount "20" @default.
• W2075955797 countsByYear W20759557972014 @default.
• W2075955797 countsByYear W20759557972015 @default.
• W2075955797 countsByYear W20759557972018 @default.
• W2075955797 countsByYear W20759557972021 @default.
• W2075955797 crossrefType "journal-article" @default.
• W2075955797 hasAuthorship W2075955797A5012917847 @default.
• W2075955797 hasAuthorship W2075955797A5027488429 @default.
• W2075955797 hasAuthorship W2075955797A5034369406 @default.
• W2075955797 hasAuthorship W2075955797A5066670744 @default.
• W2075955797 hasConcept C117961784 @default.
• W2075955797 hasConcept C121608353 @default.
• W2075955797 hasConcept C126322002 @default.
• W2075955797 hasConcept C142724271 @default.
• W2075955797 hasConcept C189165786 @default.
• W2075955797 hasConcept C204232928 @default.
• W2075955797 hasConcept C2777738151 @default.
• W2075955797 hasConcept C52124034 @default.
• W2075955797 hasConcept C530470458 @default.
• W2075955797 hasConcept C71924100 @default.
• W2075955797 hasConcept C74864618 @default.
• W2075955797 hasConcept C86492073 @default.
• W2075955797 hasConcept C86803240 @default.
• W2075955797 hasConcept C95444343 @default.
• W2075955797 hasConceptScore W2075955797C117961784 @default.
• W2075955797 hasConceptScore W2075955797C121608353 @default.
• W2075955797 hasConceptScore W2075955797C126322002 @default.
• W2075955797 hasConceptScore W2075955797C142724271 @default.
• W2075955797 hasConceptScore W2075955797C189165786 @default.
• W2075955797 hasConceptScore W2075955797C204232928 @default.
• W2075955797 hasConceptScore W2075955797C2777738151 @default.
• W2075955797 hasConceptScore W2075955797C52124034 @default.
• W2075955797 hasConceptScore W2075955797C530470458 @default.
• W2075955797 hasConceptScore W2075955797C71924100 @default.
• W2075955797 hasConceptScore W2075955797C74864618 @default.
• W2075955797 hasConceptScore W2075955797C86492073 @default.
• W2075955797 hasConceptScore W2075955797C86803240 @default.
• W2075955797 hasConceptScore W2075955797C95444343 @default.
• W2075955797 hasIssue "3" @default.
• W2075955797 hasLocation W20759557971 @default.
• W2075955797 hasLocation W20759557972 @default.
• W2075955797 hasOpenAccess W2075955797 @default.
• W2075955797 hasPrimaryLocation W20759557971 @default.
• W2075955797 hasRelatedWork W1964810899 @default.
• W2075955797 hasRelatedWork W1988297300 @default.
• W2075955797 hasRelatedWork W2021145609 @default.
• W2075955797 hasRelatedWork W2084602170 @default.
• W2075955797 hasRelatedWork W2143303285 @default.
• W2075955797 hasRelatedWork W2145064946 @default.
• W2075955797 hasRelatedWork W2747882396 @default.
• W2075955797 hasRelatedWork W2901141843 @default.
• W2075955797 hasRelatedWork W3100197996 @default.
• W2075955797 hasRelatedWork W4242915321 @default.
• W2075955797 hasVolume "79" @default.
• W2075955797 isParatext "false" @default.
• W2075955797 isRetracted "false" @default.

• next