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- W2075969871 abstract "Murine L-929 cells were treated with benzene or a series of benzene metabolites, washed and then interferon-α/β was induced with polyriboinosinic-polyribocytidylic acid. Exposure of the cells to benzene or phenol, a monocyclic metabolite of benzene, did not affect interferon-α/β induction. However, exposure of the cells to <i>p</i>-benzoquinone, hydroquinone or catechol, dihydroxy- and diketo-metabolites of benzene, resulted in a severe inhibition of interferon-α/β production. There was no significant loss of viability of the cell cultures. Additional studies with <i>p</i>-benzoquinone indicated that inhibition of interferon-α/β was reversible and could be abrogated by addition of reduced glutathione to the cell cultures." @default.
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- W2075969871 date "1989-01-01" @default.
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- W2075969871 title "Inhibition of Interferon–Alpha/Beta Induction in L-929 Cells by Benzene and Benzene Metabolites" @default.
- W2075969871 doi "https://doi.org/10.1159/000226743" @default.
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