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• W2076012302 abstract "Abstract. In 10 patients with type 1 diabetes mellitus, platelet-derived growth factor (PDGF) was assessed using an in vitro assay based on the stimulation of DNA synthesis in the 3T3 mouse fibroblast cell line. β-Thromboglobulin (β-TG) was used as an index for platelet α-granules content. Platelet β-TG content and PDGF were markedly decreased in diabetic patients while plasma β-TG was increased as compared with control subjects. In diabetic patients, a significant negative correlation was found between plasma β-TG level and β-TG total platelet content, associated with a significant positive correlation between platelet β-TG content and PDGF. These results suggest that PDGF release might be increased in diabetic subjects. This may account in part for the cell proliferation observed in diabetic angiopathy." @default.
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• W2076012302 date "1989-04-01" @default.
• W2076012302 modified "2023-10-04" @default.
• W2076012302 title "Platelet-derived growth factor (PDGF) in type 1 diabetes mellitus" @default.
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• W2076012302 doi "https://doi.org/10.1111/j.1365-2362.1989.tb00213.x" @default.
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