FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076064293> ?p ?o ?g. }

• W2076064293 endingPage "703" @default.
• W2076064293 startingPage "688" @default.
• W2076064293 abstract "All therapies currently recommended for the management of osteoporosis act mainly to inhibit bone resorption and reduce bone remodeling. PTH and its analog, teriparatide [recombinant human PTH(1-34)], represent a new class of anabolic therapies for the treatment of severe osteoporosis, having the potential to improve skeletal microarchitecture. Significant reductions in both vertebral and appendicular fracture rates have been demonstrated in the phase III trial of teriparatide, involving elderly women with at least one prevalent vertebral fracture before the onset of therapy. However, there is as yet no evidence that the antifracture efficacy of PTH will be superior to the bisphosphonates, whereas cost-utility estimates suggest that teriparatide is significantly more expensive. Teriparatide should be considered as treatment for postmenopausal women and men with severe osteoporosis, as well as for patients with established glucocorticoid-induced osteoporosis who require long-term steroid treatment. Teriparatide should also be considered for the management of individuals at particularly high risk for fractures, including subjects who are younger than age 65 and who have particularly low bone mineral density measurements (T scores < or = 3.5). Teriparatide therapy is not recommended for more than 2 yr, based, in part, on the induction of osteosarcoma in a rat model of carcinogenicity. Total daily calcium intake from both supplements and dietary sources should be limited to 1500 mg together with adequate vitamin D intake (< or =1000 U/d). Monitoring of serum calcium may be safely limited to measurement after 1 month of treatment; mild hypercalcemia may be treated by withdrawing dietary calcium supplements, reducing the dosing frequency of PTH, or both. At present, concurrent therapy with antiresorptive therapy, particularly bisphosphonates, should be avoided, although sequential therapy with such agents may consolidate the beneficial effects upon the skeleton after PTH is discontinued." @default.
• W2076064293 created "2016-06-24" @default.
• W2076064293 creator A5003143379 @default.
• W2076064293 creator A5006195793 @default.
• W2076064293 creator A5008149390 @default.
• W2076064293 creator A5011375575 @default.
• W2076064293 creator A5021940540 @default.
• W2076064293 creator A5030361963 @default.
• W2076064293 creator A5039354344 @default.
• W2076064293 creator A5042272023 @default.
• W2076064293 creator A5047122819 @default.
• W2076064293 creator A5048725197 @default.
• W2076064293 creator A5072880232 @default.
• W2076064293 creator A5080142103 @default.
• W2076064293 date "2005-03-15" @default.
• W2076064293 modified "2023-10-13" @default.
• W2076064293 title "Parathyroid Hormone and Teriparatide for the Treatment of Osteoporosis: A Review of the Evidence and Suggested Guidelines for Its Use" @default.
• W2076064293 cites W1526826623 @default.
• W2076064293 cites W1593442063 @default.
• W2076064293 cites W1913078431 @default.
• W2076064293 cites W1967910353 @default.
• W2076064293 cites W1968418396 @default.
• W2076064293 cites W1972673498 @default.
• W2076064293 cites W1976687766 @default.
• W2076064293 cites W1979462438 @default.
• W2076064293 cites W1986841828 @default.
• W2076064293 cites W1987005490 @default.
• W2076064293 cites W1988005311 @default.
• W2076064293 cites W1989400609 @default.
• W2076064293 cites W1989783674 @default.
• W2076064293 cites W1991404229 @default.
• W2076064293 cites W1992931986 @default.
• W2076064293 cites W1993088612 @default.
• W2076064293 cites W2002875528 @default.
• W2076064293 cites W2004302812 @default.
• W2076064293 cites W2005298224 @default.
• W2076064293 cites W2008147692 @default.
• W2076064293 cites W2013599591 @default.
• W2076064293 cites W2015247179 @default.
• W2076064293 cites W2021411650 @default.
• W2076064293 cites W2023781848 @default.
• W2076064293 cites W2025697454 @default.
• W2076064293 cites W2029198743 @default.
• W2076064293 cites W2030285552 @default.
• W2076064293 cites W2039548369 @default.
• W2076064293 cites W2041287840 @default.
• W2076064293 cites W2041598849 @default.
• W2076064293 cites W2044443346 @default.
• W2076064293 cites W2045947279 @default.
• W2076064293 cites W2048250502 @default.
• W2076064293 cites W2050078279 @default.
• W2076064293 cites W2050102966 @default.
• W2076064293 cites W2052991153 @default.
• W2076064293 cites W2053689432 @default.
• W2076064293 cites W2056850960 @default.
• W2076064293 cites W2057217671 @default.
• W2076064293 cites W2060433304 @default.
• W2076064293 cites W2067437525 @default.
• W2076064293 cites W2067718592 @default.
• W2076064293 cites W2078391984 @default.
• W2076064293 cites W2080112705 @default.
• W2076064293 cites W2082251318 @default.
• W2076064293 cites W2083011022 @default.
• W2076064293 cites W2083421885 @default.
• W2076064293 cites W2083593344 @default.
• W2076064293 cites W2085200136 @default.
• W2076064293 cites W2087678261 @default.
• W2076064293 cites W2092629935 @default.
• W2076064293 cites W2092654589 @default.
• W2076064293 cites W2093050601 @default.
• W2076064293 cites W2093057350 @default.
• W2076064293 cites W2093206323 @default.
• W2076064293 cites W2094937528 @default.
• W2076064293 cites W2096150705 @default.
• W2076064293 cites W2101680622 @default.
• W2076064293 cites W2102123887 @default.
• W2076064293 cites W2109617636 @default.
• W2076064293 cites W2112629831 @default.
• W2076064293 cites W2113162921 @default.
• W2076064293 cites W2113523811 @default.
• W2076064293 cites W2120292081 @default.
• W2076064293 cites W2124527463 @default.
• W2076064293 cites W2127733654 @default.
• W2076064293 cites W2127985847 @default.
• W2076064293 cites W2128195492 @default.
• W2076064293 cites W2135178867 @default.
• W2076064293 cites W2137266781 @default.
• W2076064293 cites W2137868736 @default.
• W2076064293 cites W2138900335 @default.
• W2076064293 cites W2145733834 @default.
• W2076064293 cites W2149598802 @default.
• W2076064293 cites W2153009489 @default.
• W2076064293 cites W2161837912 @default.
• W2076064293 cites W2164229113 @default.
• W2076064293 cites W2314892802 @default.
• W2076064293 cites W2335178464 @default.
• W2076064293 cites W2336678594 @default.
• W2076064293 cites W4237771509 @default.

• next