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- W2076070332 abstract "Abstract The occurence of tumor specific surface antigens in experimental systems is firmly established and evidence is accumulating for their existence on human lumor cells. Both cell and antibody mediated immune reactions against such antigens can be demonstrated. Sensitized lymphocytes and specific antibodies can also be detected in hosts with actively growing tumors. This ineffective immune response is not completely understood; the phenomenon of immunological enhancement, lack or immunosensitivity of the tumor cells may be contributing factors. Tumors induced with chemical carcinogens have individual antigens while virus induced tumors carry a virus determined surface antigen which is common for all the tumors induced by the same virus. The success of chemotherapy in Burkitt Lymphoma suggests the co-operation of immunological host defense factors. The geographical distribution of the tumor points to a viral etiology. These facts motivated extensive immunological studies which revealed that antibodies reacting with: (1) the cell membrane of cultured Burkitt cells, (2) the herpes virus harbored by such cells, (3) the antigen preparations extracted from such cells are present in sera of Burkitt, infectious mononucleosis and nasopharyngeal carcinoma patients." @default.
- W2076070332 created "2016-06-24" @default.
- W2076070332 creator A5006412648 @default.
- W2076070332 date "1970-02-01" @default.
- W2076070332 modified "2023-10-01" @default.
- W2076070332 title "The cell surface in immune response" @default.
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- W2076070332 doi "https://doi.org/10.1016/0014-2964(70)90049-6" @default.
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