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• W2076071140 abstract "The production and characterization of monoclonal antibodies against Pasteurella haemolytica serotype 1 is described. Ten monoclonal antibodies were produced and divided, on the basis of their properties, into six different groups. One produced bacteria agglutination only of P. haemolytica serotype 1. Three antibodies bound with P. haemolytica serotypes 1, 5-8 and 12 and the antigen was identified in immunoblots as lipopolysaccharide. Two antibodies bound P. haemolytica serotypes 1, 2, 5-8 and 12 and P. multocida serotypes 1-7, 9, 12, 15 and 16, recognizing an epitope present on a 29 kDa outer membrane protein. One antibody bound all P. haemolytica and P. multocida serotypes. The antigen was a hexosamine less than 30 kDa which contained a formalin sensitive epitope. One antibody bound only to P. haemolytica serotype 1 and the antigen was identified as a 66 kDa outer membrane protein. Two antibodies bound P. haemolytica serotypes 1, 2, 5-9 and 12 and the antigen, while not identified, was localized on the outer membrane. This study identified antigens which contribute to the cross-reactions among P. haemolytica and P. multocida serotypes and the antibodies may be useful in investigating the pathogenesis of pneumonic pasteurellosis." @default.
• W2076071140 created "2016-06-24" @default.
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• W2076071140 date "1992-10-01" @default.
• W2076071140 modified "2023-10-14" @default.
• W2076071140 title "A characterization of monoclonal antibodies prepared against Pasteurella haemolytica serotype 1 surface antigens" @default.
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• W2076071140 doi "https://doi.org/10.1016/0378-1135(92)90155-m" @default.
• W2076071140 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1280877" @default.
• W2076071140 hasPublicationYear "1992" @default.
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