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- W2076074089 abstract "Abstract groE bacterial mutants of E. coli have been isolated on the basis of their inability to propagate bacteriophage λ. The block exerted on λ growth has been shown to operate at the level of head assembly. Some groE mutations express pleiotropic effects, such as inability to propagate T4 and T5 or inability to form colonies at high temperature. P1 transduction experiments show that these groE mutations map at 83 min on the genetic map of E. coli and that a single mutation is responsible for the pleiotropic effects observed. At 43°C, some of the groE strains are temperature sensitive for growth and form long filamentous structures. Examination of the proteins synthesized at 43° by one of the temperature‐sensitive groE strains, groEA44, by SDS gel electrophoresis reveals a pattern of synthesis somewhat different from that exhibited by the gro + parent strain: some new bands appear, while others disappear." @default.
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- W2076074089 date "1974-01-01" @default.
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- W2076074089 title "Bacterial mutants which block phage assembly" @default.
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- W2076074089 doi "https://doi.org/10.1002/jss.400020224" @default.
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