Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076092560> ?p ?o ?g. }
- W2076092560 endingPage "342" @default.
- W2076092560 startingPage "335" @default.
- W2076092560 abstract "Purpose of review In recent years, there has been an increasing awareness of the central regulatory role of fibroblast growth factor 23 (FGF23) in mineral metabolism and its particular prominence in patients with chronic kidney disease (CKD). Recent findings FGF23 is a powerful predictor of adverse clinical outcomes in CKD that appears to be superior to existing mineral metabolism markers such as serum phosphate and parathyroid hormone. Interesting new data suggest a central role of bone health in the regulation of FGF23 secretion, whereas another important new study reported that virtually all circulating FGF23 in advanced renal failure is biologically intact. Finally, new data demonstrate the ability to alter FGF23 levels using common CKD therapies such as phosphate binders, active vitamin D, and cinacalcet. Summary Although FGF23 was originally discovered in studies of rare diseases, we expect that its primary utility in mainstream clinical practice will ultimately lie in the management of CKD. Emerging data highlight the potential of FGF23 as a novel diagnostic to identify CKD patients at the highest risk for disease progression, cardiovascular disease, and death, and those who might benefit from early phosphorus-related therapies before the onset of overt hyperphosphatemia." @default.
- W2076092560 created "2016-06-24" @default.
- W2076092560 creator A5008906136 @default.
- W2076092560 creator A5024089543 @default.
- W2076092560 date "2010-07-01" @default.
- W2076092560 modified "2023-09-23" @default.
- W2076092560 title "Recent advances in the rapidly evolving field of fibroblast growth factor 23 in chronic kidney disease" @default.
- W2076092560 cites W1964311752 @default.
- W2076092560 cites W1967918805 @default.
- W2076092560 cites W1968779137 @default.
- W2076092560 cites W1969718855 @default.
- W2076092560 cites W1973733126 @default.
- W2076092560 cites W1975988399 @default.
- W2076092560 cites W1976344984 @default.
- W2076092560 cites W1977645780 @default.
- W2076092560 cites W1978954148 @default.
- W2076092560 cites W1979425916 @default.
- W2076092560 cites W1979542010 @default.
- W2076092560 cites W1982290615 @default.
- W2076092560 cites W1982380608 @default.
- W2076092560 cites W1991218855 @default.
- W2076092560 cites W1992157366 @default.
- W2076092560 cites W1995343515 @default.
- W2076092560 cites W1996856345 @default.
- W2076092560 cites W2000048959 @default.
- W2076092560 cites W2003490678 @default.
- W2076092560 cites W2017219647 @default.
- W2076092560 cites W2021852822 @default.
- W2076092560 cites W2027418334 @default.
- W2076092560 cites W2027479037 @default.
- W2076092560 cites W2031941775 @default.
- W2076092560 cites W2037498463 @default.
- W2076092560 cites W2038393248 @default.
- W2076092560 cites W2048596181 @default.
- W2076092560 cites W2056362743 @default.
- W2076092560 cites W2057798151 @default.
- W2076092560 cites W2059022155 @default.
- W2076092560 cites W2059099969 @default.
- W2076092560 cites W2059115865 @default.
- W2076092560 cites W2060108666 @default.
- W2076092560 cites W2061659182 @default.
- W2076092560 cites W2067219678 @default.
- W2076092560 cites W2077703010 @default.
- W2076092560 cites W2080387599 @default.
- W2076092560 cites W2082069148 @default.
- W2076092560 cites W2086822373 @default.
- W2076092560 cites W2091948921 @default.
- W2076092560 cites W2092787493 @default.
- W2076092560 cites W2095948376 @default.
- W2076092560 cites W2097969657 @default.
- W2076092560 cites W2098796476 @default.
- W2076092560 cites W2098828778 @default.
- W2076092560 cites W2107207648 @default.
- W2076092560 cites W2107865114 @default.
- W2076092560 cites W2109439585 @default.
- W2076092560 cites W2111636767 @default.
- W2076092560 cites W2112521396 @default.
- W2076092560 cites W2113356410 @default.
- W2076092560 cites W2114360920 @default.
- W2076092560 cites W2120619511 @default.
- W2076092560 cites W2121600456 @default.
- W2076092560 cites W2122037712 @default.
- W2076092560 cites W2123786809 @default.
- W2076092560 cites W2124872159 @default.
- W2076092560 cites W2125383113 @default.
- W2076092560 cites W2125704877 @default.
- W2076092560 cites W2125955081 @default.
- W2076092560 cites W2132065563 @default.
- W2076092560 cites W2136719709 @default.
- W2076092560 cites W2138484848 @default.
- W2076092560 cites W2140575711 @default.
- W2076092560 cites W2143664225 @default.
- W2076092560 cites W2144418321 @default.
- W2076092560 cites W2145632027 @default.
- W2076092560 cites W2146992350 @default.
- W2076092560 cites W2151714015 @default.
- W2076092560 cites W2157448600 @default.
- W2076092560 cites W2159397492 @default.
- W2076092560 cites W2164074621 @default.
- W2076092560 cites W2166159490 @default.
- W2076092560 cites W2169437554 @default.
- W2076092560 cites W2170092490 @default.
- W2076092560 cites W4233469193 @default.
- W2076092560 doi "https://doi.org/10.1097/mnh.0b013e328338f536" @default.
- W2076092560 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20583336" @default.
- W2076092560 hasPublicationYear "2010" @default.
- W2076092560 type Work @default.
- W2076092560 sameAs 2076092560 @default.
- W2076092560 citedByCount "29" @default.
- W2076092560 countsByYear W20760925602012 @default.
- W2076092560 countsByYear W20760925602013 @default.
- W2076092560 countsByYear W20760925602014 @default.
- W2076092560 countsByYear W20760925602015 @default.
- W2076092560 countsByYear W20760925602018 @default.
- W2076092560 countsByYear W20760925602019 @default.
- W2076092560 countsByYear W20760925602020 @default.
- W2076092560 countsByYear W20760925602021 @default.
- W2076092560 countsByYear W20760925602023 @default.