FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076122873> ?p ?o ?g. }

• W2076122873 endingPage "S326" @default.
• W2076122873 startingPage "S326" @default.
• W2076122873 abstract "Introduction: Decreased bone mineral density (BMD) has been reported in children with IBD. These changes have usually been attributed to corticosteroid use. However, it is still unclear what role the disease process prior to the initiation of therapy may be contributing to these alterations. The purpose of this study was to compare the BMD and body composition of a cohort of children newly diagnosed with IBD with those of healthy sex-matched controls of similar age. Methods: Control subjects and otherwise healthy children never exposed to corticosteroids who were within three weeks of initiation of therapy for IBD underwent Dual Energy X-ray Absorptiometry (DXA, Lunar DPX-L). Lean tissue mass (g) and total body BMD (g/cm2) measurements were obtained by DXA. We assessed height (cm), weight (kg), and body mass index (BMI, kg/m2) for each subject. Data analysis was performed by Mann Whitney U and Spearman rank-order correlation. Results: Measurements were recorded on 30 (15 male; mean age 11.9y, range 5.5–16.8) steroid näive children newly diagnosed with IBD and 50 (24 male; mean age 11.5y, range 8–15.3) controls. IBD subjects had a 7% lower BMI compared to controls (17.24 ± 2.95 vs. 18.52 ± 2.37, p=0.01). Lean tissue mass was 13% lower in children with IBD (p=0.03), and BMD was 12% lower (0.918 ± 0.11 vs. 1.043 ± 0.133, p<0.001), compared to control subjects. Although not reaching statistical significance, a similar trend was noted for bone mineral content (BMC). In the IBD subjects, BMI (r=0.61; p<0.001) and lean tissue mass (r=0.74; p<0.001) correlated positively with BMD. Conclusion: Decreased BMD, lean tissue mass, and BMI are present at the time of diagnosis in steroid näive children with IBD. BMD correlates strongly with lean tissue mass and BMI. IBD appears to contribute to impaired BMD independent of steroid therapy." @default.
• W2076122873 created "2016-06-24" @default.
• W2076122873 creator A5026891957 @default.
• W2076122873 creator A5044323106 @default.
• W2076122873 creator A5044519340 @default.
• W2076122873 creator A5058101509 @default.
• W2076122873 date "2004-06-01" @default.
• W2076122873 modified "2023-09-25" @default.
• W2076122873 title "P0706 BONE MASS IS DECREASED IN STEROID NA??VE CHILDREN WITH IBD" @default.
• W2076122873 doi "https://doi.org/10.1097/00005176-200406001-00830" @default.
• W2076122873 hasPublicationYear "2004" @default.
• W2076122873 type Work @default.
• W2076122873 sameAs 2076122873 @default.
• W2076122873 citedByCount "0" @default.
• W2076122873 crossrefType "journal-article" @default.
• W2076122873 hasAuthorship W2076122873A5026891957 @default.
• W2076122873 hasAuthorship W2076122873A5044323106 @default.
• W2076122873 hasAuthorship W2076122873A5044519340 @default.
• W2076122873 hasAuthorship W2076122873A5058101509 @default.
• W2076122873 hasBestOaLocation W20761228731 @default.
• W2076122873 hasConcept C120863210 @default.
• W2076122873 hasConcept C126322002 @default.
• W2076122873 hasConcept C147583825 @default.
• W2076122873 hasConcept C2776541429 @default.
• W2076122873 hasConcept C2776886416 @default.
• W2076122873 hasConcept C2780221984 @default.
• W2076122873 hasConcept C2781440623 @default.
• W2076122873 hasConcept C65409693 @default.
• W2076122873 hasConcept C71924100 @default.
• W2076122873 hasConcept C72563966 @default.
• W2076122873 hasConcept C90924648 @default.
• W2076122873 hasConceptScore W2076122873C120863210 @default.
• W2076122873 hasConceptScore W2076122873C126322002 @default.
• W2076122873 hasConceptScore W2076122873C147583825 @default.
• W2076122873 hasConceptScore W2076122873C2776541429 @default.
• W2076122873 hasConceptScore W2076122873C2776886416 @default.
• W2076122873 hasConceptScore W2076122873C2780221984 @default.
• W2076122873 hasConceptScore W2076122873C2781440623 @default.
• W2076122873 hasConceptScore W2076122873C65409693 @default.
• W2076122873 hasConceptScore W2076122873C71924100 @default.
• W2076122873 hasConceptScore W2076122873C72563966 @default.
• W2076122873 hasConceptScore W2076122873C90924648 @default.
• W2076122873 hasIssue "Supplement 1" @default.
• W2076122873 hasLocation W20761228731 @default.
• W2076122873 hasLocation W20761228732 @default.
• W2076122873 hasOpenAccess W2076122873 @default.
• W2076122873 hasPrimaryLocation W20761228731 @default.
• W2076122873 hasRelatedWork W1965017800 @default.
• W2076122873 hasRelatedWork W2041775173 @default.
• W2076122873 hasRelatedWork W2105059085 @default.
• W2076122873 hasRelatedWork W2155835249 @default.
• W2076122873 hasRelatedWork W2313783891 @default.
• W2076122873 hasRelatedWork W2316083621 @default.
• W2076122873 hasRelatedWork W2387287060 @default.
• W2076122873 hasRelatedWork W2979931232 @default.
• W2076122873 hasRelatedWork W3097005902 @default.
• W2076122873 hasRelatedWork W1934976325 @default.
• W2076122873 hasVolume "39" @default.
• W2076122873 isParatext "false" @default.
• W2076122873 isRetracted "false" @default.
• W2076122873 magId "2076122873" @default.
• W2076122873 workType "article" @default.