FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076133500> ?p ?o ?g. }

• W2076133500 endingPage "548" @default.
• W2076133500 startingPage "543" @default.
• W2076133500 abstract "In humans and animals, corticosteroid excess is associated with impairment in declarative memory and changes in hippocampal structure. In animals, phenytoin pretreatment blocks the effects of stress on memory and hippocampal histology, although no studies have examined the use of phenytoin to prevent corticosteroid-associated memory changes in humans. Mood changes are also common with corticosteroids, but few treatment data are available. This report examines whether phenytoin can prevent mood or declarative memory changes secondary to bursts of prescription corticosteroids.Thirty-nine patients with allergies or pulmonary or rheumatologic illnesses and given systemic corticosteroid therapy were randomized to receive either phenytoin (300 mg/day) or placebo concurrently with the corticosteroids. Mood was assessed with the Hamilton Rating Scale for Depression, Young Mania Rating Scale, and Activation (ACT) subscale of the Internal State Scale; declarative memory was assessed with the Rey Auditory Verbal Learning Test (RAVLT) at baseline and after approximately 7 days of corticosteroid plus phenytoin or placebo therapy.The two groups were similar in age, gender, education, and corticosteroid dose. The phenytoin-treated group showed significantly smaller increases on the ACT, a mania self-report scale, than the placebo-treated group. Groups did not differ significantly on RAVLT change scores.This is the first placebo-controlled study to examine whether a medication can prevent mood and memory changes secondary to corticosteroids. Phenytoin blocked the hypomanic effects of prescription corticosteroids; however, phenytoin did not block the declarative memory effects of corticosteroids." @default.
• W2076133500 created "2016-06-24" @default.
• W2076133500 creator A5006012733 @default.
• W2076133500 creator A5024093377 @default.
• W2076133500 creator A5029047234 @default.
• W2076133500 creator A5029626426 @default.
• W2076133500 creator A5035103174 @default.
• W2076133500 creator A5044035845 @default.
• W2076133500 creator A5044527553 @default.
• W2076133500 creator A5072758977 @default.
• W2076133500 creator A5072954257 @default.
• W2076133500 creator A5073567176 @default.
• W2076133500 creator A5075547679 @default.
• W2076133500 creator A5084343783 @default.
• W2076133500 creator A5084548089 @default.
• W2076133500 creator A5088079146 @default.
• W2076133500 date "2005-03-01" @default.
• W2076133500 modified "2023-09-25" @default.
• W2076133500 title "Effect of phenytoin on mood and declarative memory during prescription corticosteroid therapy" @default.
• W2076133500 cites W1573050736 @default.
• W2076133500 cites W1596912882 @default.
• W2076133500 cites W1804267428 @default.
• W2076133500 cites W1965396609 @default.
• W2076133500 cites W1974629262 @default.
• W2076133500 cites W1975528560 @default.
• W2076133500 cites W1977249405 @default.
• W2076133500 cites W1981724466 @default.
• W2076133500 cites W1987840185 @default.
• W2076133500 cites W1988983060 @default.
• W2076133500 cites W1997253011 @default.
• W2076133500 cites W2000876197 @default.
• W2076133500 cites W2009242096 @default.
• W2076133500 cites W2011902959 @default.
• W2076133500 cites W2017748225 @default.
• W2076133500 cites W2022579442 @default.
• W2076133500 cites W2025260078 @default.
• W2076133500 cites W2025468569 @default.
• W2076133500 cites W2027066838 @default.
• W2076133500 cites W2029254303 @default.
• W2076133500 cites W2029404396 @default.
• W2076133500 cites W2032645268 @default.
• W2076133500 cites W2056225700 @default.
• W2076133500 cites W2058100086 @default.
• W2076133500 cites W2060372677 @default.
• W2076133500 cites W2061378977 @default.
• W2076133500 cites W2065797497 @default.
• W2076133500 cites W2071820126 @default.
• W2076133500 cites W2079014559 @default.
• W2076133500 cites W2089435641 @default.
• W2076133500 cites W2090976027 @default.
• W2076133500 cites W2091264006 @default.
• W2076133500 cites W2092430230 @default.
• W2076133500 cites W2102640246 @default.
• W2076133500 cites W2114613490 @default.
• W2076133500 cites W2147424766 @default.
• W2076133500 cites W2152863073 @default.
• W2076133500 cites W2167659819 @default.
• W2076133500 cites W2171524950 @default.
• W2076133500 cites W2340267567 @default.
• W2076133500 cites W2418336437 @default.
• W2076133500 cites W4319425380 @default.
• W2076133500 doi "https://doi.org/10.1016/j.biopsych.2004.11.021" @default.
• W2076133500 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15737670" @default.
• W2076133500 hasPublicationYear "2005" @default.
• W2076133500 type Work @default.
• W2076133500 sameAs 2076133500 @default.
• W2076133500 citedByCount "31" @default.
• W2076133500 countsByYear W20761335002012 @default.
• W2076133500 countsByYear W20761335002013 @default.
• W2076133500 countsByYear W20761335002014 @default.
• W2076133500 countsByYear W20761335002015 @default.
• W2076133500 countsByYear W20761335002016 @default.
• W2076133500 countsByYear W20761335002018 @default.
• W2076133500 countsByYear W20761335002019 @default.
• W2076133500 countsByYear W20761335002021 @default.
• W2076133500 countsByYear W20761335002022 @default.
• W2076133500 crossrefType "journal-article" @default.
• W2076133500 hasAuthorship W2076133500A5006012733 @default.
• W2076133500 hasAuthorship W2076133500A5024093377 @default.
• W2076133500 hasAuthorship W2076133500A5029047234 @default.
• W2076133500 hasAuthorship W2076133500A5029626426 @default.
• W2076133500 hasAuthorship W2076133500A5035103174 @default.
• W2076133500 hasAuthorship W2076133500A5044035845 @default.
• W2076133500 hasAuthorship W2076133500A5044527553 @default.
• W2076133500 hasAuthorship W2076133500A5072758977 @default.
• W2076133500 hasAuthorship W2076133500A5072954257 @default.
• W2076133500 hasAuthorship W2076133500A5073567176 @default.
• W2076133500 hasAuthorship W2076133500A5075547679 @default.
• W2076133500 hasAuthorship W2076133500A5084343783 @default.
• W2076133500 hasAuthorship W2076133500A5084548089 @default.
• W2076133500 hasAuthorship W2076133500A5088079146 @default.
• W2076133500 hasConcept C118552586 @default.
• W2076133500 hasConcept C126322002 @default.
• W2076133500 hasConcept C142724271 @default.
• W2076133500 hasConcept C15744967 @default.
• W2076133500 hasConcept C204787440 @default.
• W2076133500 hasConcept C27081682 @default.
• W2076133500 hasConcept C2776174506 @default.

• next