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- W2076137325 endingPage "1139" @default.
- W2076137325 startingPage "1119" @default.
- W2076137325 abstract "The Bacillus cereus sensu lato group contains diverse Gram-positive spore-forming bacteria that can cause gastrointestinal diseases and severe eye infections in humans. They have also been incriminated in a multitude of other severe, and frequently fatal, clinical infections, such as osteomyelitis, septicaemia, pneumonia, liver abscess and meningitis, particularly in immuno-compromised patients and preterm neonates. The pathogenic properties of this organism are mediated by the synergistic effects of a number of virulence products that promote intestinal cell destruction and/or resistance to the host immune system. This review focuses on the pore-forming haemolysins produced by B. cereus: haemolysin I (cereolysin O), haemolysin II, haemolysin III and haemolysin IV (CytK). Haemolysin I belongs to the cholesterol-dependent cytolysin (CDC) family whose best known members are listeriolysin O and perfringolysin O, produced by L. monocytogenes and C. perfringens respectively. HlyII and CytK are oligomeric ß-barrel pore-forming toxins related to the α-toxin of S. aureus or the ß-toxin of C. perfringens. The structure of haemolysin III, the least characterized haemolytic toxin from the B. cereus, group has not yet been determined." @default.
- W2076137325 created "2016-06-24" @default.
- W2076137325 creator A5052885886 @default.
- W2076137325 creator A5077569612 @default.
- W2076137325 date "2013-06-07" @default.
- W2076137325 modified "2023-10-03" @default.
- W2076137325 title "The Pore-Forming Haemolysins of Bacillus Cereus: A Review" @default.
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