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- W2076142816 abstract "The possible mode of action of the lately demonstrated steroid effect on the immediate type allergic reaction was investigated. The influence of a topical steroid, budesonide, on the effects that released mediators have on the nasal mucosa was also studied. A nasal histamine challenge study was performed in a double-blind. cross-over fashion, a 1-weck. Pretreatment with budesonide or placebo preceding the challenge. Symptoms were recorded by means of symptom score as well as objectively via rhinomanometry. In contrast to a previous allergen challenge study, the steroid was found to have minimal effect on the histamine-induced nasal symptoms. It is therefore concluded that other modes of steroid action must also be involved lin the steroid effect on the immediate type allergic reaction." @default.
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- W2076142816 date "1982-07-01" @default.
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- W2076142816 title "Budesonide and Nasal Histamine Challenge" @default.
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- W2076142816 doi "https://doi.org/10.1111/j.1398-9995.1982.tb01922.x" @default.
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