Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076152448> ?p ?o ?g. }
- W2076152448 endingPage "204" @default.
- W2076152448 startingPage "197" @default.
- W2076152448 abstract "Chronic obstructive pulmonary disease (COPD) is the most common chronic lung disease and is an important cause of morbidity worldwide. The aim of this study was to evaluate whether pulmonary rehabilitation (PR) improves the oxidant/antioxidant imbalance, exercise capacity and health-related quality of life (HRQL) in patients with different stages of COPD. Eighteen stable COPD patients participated in 8-week PR; the exercise intensity was set at 70% of the VO2 peak. Subjects were divided into 2 groups: moderate to severe (stages II/III: n = 12) and very severe COPD with FEV1 < 30% predicted (stage IV: n = 6). In patients at stages II/III, PR improved exercise capacity (6-minute walking test: 431.2 ± 26.6 vs. 489.1 ± 26.5 m, P < 0.01 and shuttle walking test: 329.2 ± 41.4 vs. 378.2 ± 41.5 m, P < 0.01) and HRQL, whereas no significant change was observed in erythrocyte lipid peroxidation and urinary 8-hydroxydeoxyguanosine, a marker for DNA damage. In contrast, PR for stage IV patients did not improve exercise capacity and HRQL, but significantly increased urinary 8-hydroxydeoxyguanosine (14.5 ± 1.7 vs. 24.3 ± 2.6 ng/mg Cr, P < 0.05). In both groups, erythrocyte antioxidants (superoxide dismutase, glutathione peroxidase, and catalase) did not change significantly after PR. Thus, urinary 8-hydroxydeoxyguanosine is a useful indicator for the PR-induced oxidative stress in COPD patients. In conclusion, appropriate exercise program in COPD patients can improve exercise capacity and HRQL without further increase of oxidative stress. However, PR for very severe COPD patients enhanced exercise-induced oxidative stress." @default.
- W2076152448 created "2016-06-24" @default.
- W2076152448 creator A5000210852 @default.
- W2076152448 creator A5002731286 @default.
- W2076152448 creator A5017740721 @default.
- W2076152448 creator A5039390248 @default.
- W2076152448 creator A5078719720 @default.
- W2076152448 date "2014-01-01" @default.
- W2076152448 modified "2023-10-03" @default.
- W2076152448 title "Urinary 8-Hydroxydeoxyguanosine Is a Potential Indicator for Estimating Pulmonary Rehabilitation-Induced Oxidative Stress in COPD Patients" @default.
- W2076152448 cites W1027091479 @default.
- W2076152448 cites W1030653330 @default.
- W2076152448 cites W1633703614 @default.
- W2076152448 cites W191793640 @default.
- W2076152448 cites W1976419152 @default.
- W2076152448 cites W1983310681 @default.
- W2076152448 cites W1994153149 @default.
- W2076152448 cites W1996103570 @default.
- W2076152448 cites W2029684018 @default.
- W2076152448 cites W2039493835 @default.
- W2076152448 cites W2042286237 @default.
- W2076152448 cites W2044803705 @default.
- W2076152448 cites W2045827836 @default.
- W2076152448 cites W2051124533 @default.
- W2076152448 cites W2052977441 @default.
- W2076152448 cites W2057304386 @default.
- W2076152448 cites W2071805440 @default.
- W2076152448 cites W2079321364 @default.
- W2076152448 cites W2080710138 @default.
- W2076152448 cites W2083436606 @default.
- W2076152448 cites W2086410495 @default.
- W2076152448 cites W2090389306 @default.
- W2076152448 cites W2098142497 @default.
- W2076152448 cites W2111736273 @default.
- W2076152448 cites W2123848794 @default.
- W2076152448 cites W2127951128 @default.
- W2076152448 cites W2135819121 @default.
- W2076152448 cites W2137679877 @default.
- W2076152448 cites W2140806188 @default.
- W2076152448 cites W2141055635 @default.
- W2076152448 cites W2146985504 @default.
- W2076152448 cites W2148123503 @default.
- W2076152448 cites W2149296107 @default.
- W2076152448 cites W2158169335 @default.
- W2076152448 cites W2162376947 @default.
- W2076152448 cites W2182061238 @default.
- W2076152448 cites W2604596332 @default.
- W2076152448 cites W3078121364 @default.
- W2076152448 cites W3215332570 @default.
- W2076152448 doi "https://doi.org/10.1620/tjem.233.197" @default.
- W2076152448 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25018154" @default.
- W2076152448 hasPublicationYear "2014" @default.
- W2076152448 type Work @default.
- W2076152448 sameAs 2076152448 @default.
- W2076152448 citedByCount "3" @default.
- W2076152448 countsByYear W20761524482015 @default.
- W2076152448 countsByYear W20761524482021 @default.
- W2076152448 crossrefType "journal-article" @default.
- W2076152448 hasAuthorship W2076152448A5000210852 @default.
- W2076152448 hasAuthorship W2076152448A5002731286 @default.
- W2076152448 hasAuthorship W2076152448A5017740721 @default.
- W2076152448 hasAuthorship W2076152448A5039390248 @default.
- W2076152448 hasAuthorship W2076152448A5078719720 @default.
- W2076152448 hasBestOaLocation W20761524481 @default.
- W2076152448 hasConcept C126322002 @default.
- W2076152448 hasConcept C1862650 @default.
- W2076152448 hasConcept C2775838275 @default.
- W2076152448 hasConcept C2776151105 @default.
- W2076152448 hasConcept C2776780178 @default.
- W2076152448 hasConcept C2778760513 @default.
- W2076152448 hasConcept C2780779891 @default.
- W2076152448 hasConcept C2780829032 @default.
- W2076152448 hasConcept C71924100 @default.
- W2076152448 hasConcept C77411442 @default.
- W2076152448 hasConcept C90924648 @default.
- W2076152448 hasConceptScore W2076152448C126322002 @default.
- W2076152448 hasConceptScore W2076152448C1862650 @default.
- W2076152448 hasConceptScore W2076152448C2775838275 @default.
- W2076152448 hasConceptScore W2076152448C2776151105 @default.
- W2076152448 hasConceptScore W2076152448C2776780178 @default.
- W2076152448 hasConceptScore W2076152448C2778760513 @default.
- W2076152448 hasConceptScore W2076152448C2780779891 @default.
- W2076152448 hasConceptScore W2076152448C2780829032 @default.
- W2076152448 hasConceptScore W2076152448C71924100 @default.
- W2076152448 hasConceptScore W2076152448C77411442 @default.
- W2076152448 hasConceptScore W2076152448C90924648 @default.
- W2076152448 hasIssue "3" @default.
- W2076152448 hasLocation W20761524481 @default.
- W2076152448 hasLocation W20761524482 @default.
- W2076152448 hasLocation W20761524483 @default.
- W2076152448 hasOpenAccess W2076152448 @default.
- W2076152448 hasPrimaryLocation W20761524481 @default.
- W2076152448 hasRelatedWork W1989966358 @default.
- W2076152448 hasRelatedWork W2003518555 @default.
- W2076152448 hasRelatedWork W2038022415 @default.
- W2076152448 hasRelatedWork W2056466478 @default.
- W2076152448 hasRelatedWork W2141253642 @default.
- W2076152448 hasRelatedWork W2146857062 @default.