Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076156048> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2076156048 endingPage "288" @default.
- W2076156048 startingPage "277" @default.
- W2076156048 abstract "Increased permeability of the vascular endothelium is a critical part of pathological processes such as inflammation and wound healing. While several cytokines have been shown to increase endothelial permeability, none has been shown to reduce it. We studied the effect of interferon-alpha 2b on the barrier function of bovine retinal capillary endothelial cells in vitro and found that it increased the electrical resistance of the monolayers (treated cells 211 +/- 6 ohm.cm2, untreated 109 +/- 14 ohm.cm2), decreased their permeability to inulin (Pc inulin of untreated cells 0.73 +/- 0.21 x 10(-6) cm/sec, treated 0.31 +/- 0.23 x 10(-6) cm/sec, P = 0.015), and enhanced their morphological differentiation. Interferon-gamma had no effect. No effect of interferon-alpha treatment on the permeability of bovine aortic endothelial cells was found. We conclude that interferon-alpha 2b can enhance the barrier function of retinal microvascular endothelium in vitro. This is consistent with the hypothesis that interferon-alpha is an effector of a mechanism which actively promotes tissue homeostasis and suggests that it might have therapeutic potential in diseases characterized by leakage of the vascular endothelium." @default.
- W2076156048 created "2016-06-24" @default.
- W2076156048 creator A5001215128 @default.
- W2076156048 creator A5007592619 @default.
- W2076156048 date "1995-05-01" @default.
- W2076156048 modified "2023-10-14" @default.
- W2076156048 title "Interferon-α 2b Enhances Barrier Function of Bovine Retinal Microvascular Endothelium in Vitro" @default.
- W2076156048 doi "https://doi.org/10.1006/mvre.1995.1024" @default.
- W2076156048 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7643749" @default.
- W2076156048 hasPublicationYear "1995" @default.
- W2076156048 type Work @default.
- W2076156048 sameAs 2076156048 @default.
- W2076156048 citedByCount "52" @default.
- W2076156048 countsByYear W20761560482012 @default.
- W2076156048 countsByYear W20761560482013 @default.
- W2076156048 countsByYear W20761560482016 @default.
- W2076156048 countsByYear W20761560482017 @default.
- W2076156048 countsByYear W20761560482018 @default.
- W2076156048 countsByYear W20761560482019 @default.
- W2076156048 countsByYear W20761560482020 @default.
- W2076156048 countsByYear W20761560482021 @default.
- W2076156048 countsByYear W20761560482022 @default.
- W2076156048 countsByYear W20761560482023 @default.
- W2076156048 crossrefType "journal-article" @default.
- W2076156048 hasAuthorship W2076156048A5001215128 @default.
- W2076156048 hasAuthorship W2076156048A5007592619 @default.
- W2076156048 hasConcept C113045295 @default.
- W2076156048 hasConcept C123012128 @default.
- W2076156048 hasConcept C134018914 @default.
- W2076156048 hasConcept C185592680 @default.
- W2076156048 hasConcept C202751555 @default.
- W2076156048 hasConcept C203014093 @default.
- W2076156048 hasConcept C2776178377 @default.
- W2076156048 hasConcept C2776914184 @default.
- W2076156048 hasConcept C2776992346 @default.
- W2076156048 hasConcept C2778690821 @default.
- W2076156048 hasConcept C51911345 @default.
- W2076156048 hasConcept C55493867 @default.
- W2076156048 hasConcept C86803240 @default.
- W2076156048 hasConcept C95444343 @default.
- W2076156048 hasConceptScore W2076156048C113045295 @default.
- W2076156048 hasConceptScore W2076156048C123012128 @default.
- W2076156048 hasConceptScore W2076156048C134018914 @default.
- W2076156048 hasConceptScore W2076156048C185592680 @default.
- W2076156048 hasConceptScore W2076156048C202751555 @default.
- W2076156048 hasConceptScore W2076156048C203014093 @default.
- W2076156048 hasConceptScore W2076156048C2776178377 @default.
- W2076156048 hasConceptScore W2076156048C2776914184 @default.
- W2076156048 hasConceptScore W2076156048C2776992346 @default.
- W2076156048 hasConceptScore W2076156048C2778690821 @default.
- W2076156048 hasConceptScore W2076156048C51911345 @default.
- W2076156048 hasConceptScore W2076156048C55493867 @default.
- W2076156048 hasConceptScore W2076156048C86803240 @default.
- W2076156048 hasConceptScore W2076156048C95444343 @default.
- W2076156048 hasIssue "3" @default.
- W2076156048 hasLocation W20761560481 @default.
- W2076156048 hasLocation W20761560482 @default.
- W2076156048 hasOpenAccess W2076156048 @default.
- W2076156048 hasPrimaryLocation W20761560481 @default.
- W2076156048 hasRelatedWork W1163901755 @default.
- W2076156048 hasRelatedWork W1997871151 @default.
- W2076156048 hasRelatedWork W2057602456 @default.
- W2076156048 hasRelatedWork W2087300502 @default.
- W2076156048 hasRelatedWork W2088313191 @default.
- W2076156048 hasRelatedWork W2088393488 @default.
- W2076156048 hasRelatedWork W2898197629 @default.
- W2076156048 hasRelatedWork W4225385429 @default.
- W2076156048 hasRelatedWork W4313373333 @default.
- W2076156048 hasRelatedWork W4318960514 @default.
- W2076156048 hasVolume "49" @default.
- W2076156048 isParatext "false" @default.
- W2076156048 isRetracted "false" @default.
- W2076156048 magId "2076156048" @default.
- W2076156048 workType "article" @default.