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- W2076157872 abstract "A novel series of 3-(2-furyl)acrylate monosaccharide esters Ia–f and menthyloxycarbonyl monosaccharide esters IIa–f were designed and synthesized. The chemical structures of the target compounds were confirmed by IR, ¹H- and ¹³C-NMR and ESI-MS, and the target compounds were investigated for their in vitro antibacterial and antifungal activities. The antibacterial screening results showed that the 3-(2-furyl)acrylate monosaccharide ester derivatives Ia–f were either inactive or only weakly active against the three Gram-positive bacterial strains tested, whereas the menthyloxycarbonyl monosaccharide ester derivatives IIa–f exhibited higher levels of activity, with compound IIe being especially potent. The results of the antifungal screening revealed that compounds Ib, Ie, IIb and IIc displayed potent in vitro activities, whereas If and IIf showed promising activities against all of the microorganisms tested, with If exhibiting levels of activity deserving of further investigation." @default.
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- W2076157872 date "2012-07-23" @default.
- W2076157872 modified "2023-09-29" @default.
- W2076157872 title "Synthesis, Characterization, Antibacterial and Antifungal Evaluation of Novel Monosaccharide Esters" @default.
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- W2076157872 doi "https://doi.org/10.3390/molecules17078661" @default.
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