Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076169395> ?p ?o ?g. }
- W2076169395 endingPage "F776" @default.
- W2076169395 startingPage "F757" @default.
- W2076169395 abstract "Chronic kidney disease (CKD) has become a serious public health problem because of its associated morbidity, premature mortality, and attendant healthcare costs. The rising number of persons with CKD is linked with the aging population structure and an increased prevalence of diabetes, hypertension, and obesity. There is an inherited risk associated with developing CKD, as evidenced by familial clustering and differing prevalence rates across ethnic groups. Previous studies to determine the inherited risk factors for CKD rarely identified genetic variants that were robustly replicated. However, improvements in genotyping technologies and analytic methods are now helping to identify promising genetic loci aided by international collaboration and multiconsortia efforts. More recently, epigenetic modifications have been proposed to play a role in both the inherited susceptibility to CKD and, importantly, to explain how the environment dynamically interacts with the genome to alter an individual's disease risk. Genome-wide, epigenome-wide, and whole transcriptome studies have been performed, and optimal approaches for integrative analysis are being developed. This review summarizes recent research and the current status of genetic and epigenetic risk factors influencing CKD using population-based information." @default.
- W2076169395 created "2016-06-24" @default.
- W2076169395 creator A5023452243 @default.
- W2076169395 creator A5037199781 @default.
- W2076169395 creator A5062393855 @default.
- W2076169395 creator A5067092840 @default.
- W2076169395 date "2014-10-01" @default.
- W2076169395 modified "2023-10-17" @default.
- W2076169395 title "Genetic and epigenetic factors influencing chronic kidney disease" @default.
- W2076169395 cites W1520066951 @default.
- W2076169395 cites W1570583414 @default.
- W2076169395 cites W1582296481 @default.
- W2076169395 cites W1855576760 @default.
- W2076169395 cites W1964061603 @default.
- W2076169395 cites W1964103367 @default.
- W2076169395 cites W1967490910 @default.
- W2076169395 cites W1967550939 @default.
- W2076169395 cites W1975847255 @default.
- W2076169395 cites W1977088964 @default.
- W2076169395 cites W1980453073 @default.
- W2076169395 cites W1981189656 @default.
- W2076169395 cites W1994501150 @default.
- W2076169395 cites W1997314757 @default.
- W2076169395 cites W1997849573 @default.
- W2076169395 cites W2000541664 @default.
- W2076169395 cites W2000744599 @default.
- W2076169395 cites W2001260124 @default.
- W2076169395 cites W2004731491 @default.
- W2076169395 cites W2005885315 @default.
- W2076169395 cites W2008317079 @default.
- W2076169395 cites W2012851990 @default.
- W2076169395 cites W2013443536 @default.
- W2076169395 cites W2022258892 @default.
- W2076169395 cites W2022351036 @default.
- W2076169395 cites W2023491353 @default.
- W2076169395 cites W2026182597 @default.
- W2076169395 cites W2028407140 @default.
- W2076169395 cites W2028473545 @default.
- W2076169395 cites W2030527067 @default.
- W2076169395 cites W2031017520 @default.
- W2076169395 cites W2036632755 @default.
- W2076169395 cites W2039597156 @default.
- W2076169395 cites W2040829316 @default.
- W2076169395 cites W2042103448 @default.
- W2076169395 cites W2043334354 @default.
- W2076169395 cites W2043575472 @default.
- W2076169395 cites W2044226004 @default.
- W2076169395 cites W2044839731 @default.
- W2076169395 cites W2046649415 @default.
- W2076169395 cites W2048048723 @default.
- W2076169395 cites W2048740425 @default.
- W2076169395 cites W2049066398 @default.
- W2076169395 cites W2049701327 @default.
- W2076169395 cites W2050074594 @default.
- W2076169395 cites W2051882044 @default.
- W2076169395 cites W2052829630 @default.
- W2076169395 cites W2053102671 @default.
- W2076169395 cites W2055864845 @default.
- W2076169395 cites W2056693113 @default.
- W2076169395 cites W2058286579 @default.
- W2076169395 cites W2058367373 @default.
- W2076169395 cites W2061477448 @default.
- W2076169395 cites W2061810285 @default.
- W2076169395 cites W2063369009 @default.
- W2076169395 cites W2063848155 @default.
- W2076169395 cites W2065279621 @default.
- W2076169395 cites W2072026981 @default.
- W2076169395 cites W2074017816 @default.
- W2076169395 cites W2074921359 @default.
- W2076169395 cites W2076100820 @default.
- W2076169395 cites W2078758369 @default.
- W2076169395 cites W2079362912 @default.
- W2076169395 cites W2079501979 @default.
- W2076169395 cites W2083272036 @default.
- W2076169395 cites W2084320878 @default.
- W2076169395 cites W2085941424 @default.
- W2076169395 cites W2086799994 @default.
- W2076169395 cites W2088912491 @default.
- W2076169395 cites W2090234003 @default.
- W2076169395 cites W2095746901 @default.
- W2076169395 cites W2097148864 @default.
- W2076169395 cites W2097628596 @default.
- W2076169395 cites W2099739381 @default.
- W2076169395 cites W2100076924 @default.
- W2076169395 cites W2102646996 @default.
- W2076169395 cites W2103473783 @default.
- W2076169395 cites W2103504539 @default.
- W2076169395 cites W2105314711 @default.
- W2076169395 cites W2105806989 @default.
- W2076169395 cites W2106137223 @default.
- W2076169395 cites W2106447997 @default.
- W2076169395 cites W2106907719 @default.
- W2076169395 cites W2107814424 @default.
- W2076169395 cites W2108525019 @default.
- W2076169395 cites W2110336660 @default.
- W2076169395 cites W2111285312 @default.
- W2076169395 cites W2111663222 @default.
- W2076169395 cites W2111707748 @default.