FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076171836> ?p ?o ?g. }

• W2076171836 endingPage "147" @default.
• W2076171836 startingPage "141" @default.
• W2076171836 abstract "Abnormalities in circadian rhythms are prominent features of bipolar disorder. Disrupted circadian rhythms are associated with an increased risk of relapse in bipolar disorder. Normalizing the circadian rhythm pattern of bipolar patients may improve their sleep and lead to fewer mood exacerbations. This study evaluated adjunctive ramelteon for the treatment of insomnia and mood stability in euthymic bipolar patients. Participants with euthymic bipolar disorder and sleep disturbances were randomized to receive adjunctive ramelteon or placebo in addition to their regular psychiatric medications for up to 24 weeks or until they experienced a relapse (defined as a depressed or manic event). 83 participants were randomized to receive ramelteon (n=42) or placebo (n=41). Forty participants relapsed (48.2%). Cox regression analyses indicated that participants who received ramelteon (odds ratio 0.48, p=.024) were less likely to relapse. Kaplan Meier curves also indicated longer median survival times in the ramelteon group (Mdn=188 days) versus the placebo group (Mdn=84 days) X2(1)=5.33, p=.02. There were no serious adverse events in this study. This was a small study with only 83 participants. The one-week window of confirmed stability is shorter than time intervals used in other studies. The present study shows that ramelteon was effective in maintaining stability for individuals with bipolar disorder. Patients treated with ramelteon were approximately half as likely to relapse as patients treated with placebo throughout the 24-week treatment period." @default.
• W2076171836 created "2016-06-24" @default.
• W2076171836 creator A5007028019 @default.
• W2076171836 creator A5026919811 @default.
• W2076171836 creator A5031967771 @default.
• W2076171836 creator A5037320880 @default.
• W2076171836 creator A5061520222 @default.
• W2076171836 creator A5075143247 @default.
• W2076171836 creator A5078637920 @default.
• W2076171836 date "2013-01-01" @default.
• W2076171836 modified "2023-10-13" @default.
• W2076171836 title "A double-blind, randomized, placebo-controlled trial of adjunctive ramelteon for the treatment of insomnia and mood stability in patients with euthymic bipolar disorder" @default.
• W2076171836 cites W1594539812 @default.
• W2076171836 cites W1872127900 @default.
• W2076171836 cites W1972519055 @default.
• W2076171836 cites W1974592061 @default.
• W2076171836 cites W1982469223 @default.
• W2076171836 cites W1989460808 @default.
• W2076171836 cites W2013987967 @default.
• W2076171836 cites W2019955714 @default.
• W2076171836 cites W2031809759 @default.
• W2076171836 cites W2037136952 @default.
• W2076171836 cites W2065962732 @default.
• W2076171836 cites W2070311733 @default.
• W2076171836 cites W2077027462 @default.
• W2076171836 cites W2080229560 @default.
• W2076171836 cites W2081397150 @default.
• W2076171836 cites W2102924552 @default.
• W2076171836 cites W2131823335 @default.
• W2076171836 cites W2135399947 @default.
• W2076171836 cites W2142490107 @default.
• W2076171836 cites W2145141773 @default.
• W2076171836 cites W2151487996 @default.
• W2076171836 cites W2163640551 @default.
• W2076171836 cites W2167659819 @default.
• W2076171836 cites W4297914005 @default.
• W2076171836 doi "https://doi.org/10.1016/j.jad.2012.06.023" @default.
• W2076171836 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22963894" @default.
• W2076171836 hasPublicationYear "2013" @default.
• W2076171836 type Work @default.
• W2076171836 sameAs 2076171836 @default.
• W2076171836 citedByCount "61" @default.
• W2076171836 countsByYear W20761718362013 @default.
• W2076171836 countsByYear W20761718362014 @default.
• W2076171836 countsByYear W20761718362015 @default.
• W2076171836 countsByYear W20761718362016 @default.
• W2076171836 countsByYear W20761718362017 @default.
• W2076171836 countsByYear W20761718362018 @default.
• W2076171836 countsByYear W20761718362019 @default.
• W2076171836 countsByYear W20761718362020 @default.
• W2076171836 countsByYear W20761718362021 @default.
• W2076171836 countsByYear W20761718362022 @default.
• W2076171836 countsByYear W20761718362023 @default.
• W2076171836 crossrefType "journal-article" @default.
• W2076171836 hasAuthorship W2076171836A5007028019 @default.
• W2076171836 hasAuthorship W2076171836A5026919811 @default.
• W2076171836 hasAuthorship W2076171836A5031967771 @default.
• W2076171836 hasAuthorship W2076171836A5037320880 @default.
• W2076171836 hasAuthorship W2076171836A5061520222 @default.
• W2076171836 hasAuthorship W2076171836A5075143247 @default.
• W2076171836 hasAuthorship W2076171836A5078637920 @default.
• W2076171836 hasConcept C118552586 @default.
• W2076171836 hasConcept C126322002 @default.
• W2076171836 hasConcept C142724271 @default.
• W2076171836 hasConcept C15744967 @default.
• W2076171836 hasConcept C168563851 @default.
• W2076171836 hasConcept C204787440 @default.
• W2076171836 hasConcept C27081682 @default.
• W2076171836 hasConcept C2776174506 @default.
• W2076171836 hasConcept C2776809841 @default.
• W2076171836 hasConcept C2778609679 @default.
• W2076171836 hasConcept C2780550438 @default.
• W2076171836 hasConcept C2780733359 @default.
• W2076171836 hasConcept C42219234 @default.
• W2076171836 hasConcept C71924100 @default.
• W2076171836 hasConceptScore W2076171836C118552586 @default.
• W2076171836 hasConceptScore W2076171836C126322002 @default.
• W2076171836 hasConceptScore W2076171836C142724271 @default.
• W2076171836 hasConceptScore W2076171836C15744967 @default.
• W2076171836 hasConceptScore W2076171836C168563851 @default.
• W2076171836 hasConceptScore W2076171836C204787440 @default.
• W2076171836 hasConceptScore W2076171836C27081682 @default.
• W2076171836 hasConceptScore W2076171836C2776174506 @default.
• W2076171836 hasConceptScore W2076171836C2776809841 @default.
• W2076171836 hasConceptScore W2076171836C2778609679 @default.
• W2076171836 hasConceptScore W2076171836C2780550438 @default.
• W2076171836 hasConceptScore W2076171836C2780733359 @default.
• W2076171836 hasConceptScore W2076171836C42219234 @default.
• W2076171836 hasConceptScore W2076171836C71924100 @default.
• W2076171836 hasIssue "1-2" @default.
• W2076171836 hasLocation W20761718361 @default.
• W2076171836 hasLocation W20761718362 @default.
• W2076171836 hasOpenAccess W2076171836 @default.
• W2076171836 hasPrimaryLocation W20761718361 @default.
• W2076171836 hasRelatedWork W1971140546 @default.
• W2076171836 hasRelatedWork W1971818407 @default.
• W2076171836 hasRelatedWork W2005862222 @default.
• W2076171836 hasRelatedWork W2034286927 @default.

• next