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• W2076173001 abstract "Background Common marmosets (Callithrix jacchus) are susceptible to gastrointestinal diseases. Sensitivity to nutritional elements, for example gluten, has been suggested, but a serological screening has not been performed yet. Methods A gluten-containing diet was offered to 24 animals, followed by a gluten-free diet. During these diets, serum IgA antibodies to gliadin (AGA), tissue transglutaminase (tTG), deamidated gliadin (ADGA), and glycoprotein 2 (AGP2A) were determined. Body weight, diarrhea, and other clinical symptoms were recorded. Results Gluten increased AGA, tTG, and AGP2A concentrations in 13 of 24 animals. A significant decline of AGA and AGP2A was seen on gluten withdrawal. Positive (AGA, tTG) animals presented diarrhea more frequently on gluten-containing diet and showed significantly increased body weight on gluten-free diet compared to negative animals. Conclusion Gluten ingestion caused gastrointestinal symptoms in common marmosets, which disappeared on gluten withdrawal. Considering the immunological response to both diets, gluten sensitivity seems to be most likely." @default.
• W2076173001 created "2016-06-24" @default.
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• W2076173001 date "2013-05-25" @default.
• W2076173001 modified "2023-10-16" @default.
• W2076173001 title "The influence of gluten on clinical and immunological status of common marmosets (<i>Callithrix jacchus</i> )" @default.
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• W2076173001 doi "https://doi.org/10.1111/jmp.12055" @default.
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